Michigan Wolverines vs Michigan State Spartans Prediction, 10/25/2025 College Football Picks, Best Bets & Odds

Game: Michigan Wolverines vs Michigan State Spartans

Date: Saturday, October 25, 2025

Location: Spartan Stadium in East Lansing, MI

TV: NBC

Odds/Point Spread: Spartans (+14.0)

Total/Over-Under: 48

The Michigan State Spartans (3-4) will try to defeat the Michigan Wolverines (5-2) at Spartan Stadium on Saturday, October 25, 2025. Michigan State opens this matchup as 14.0-point dogs. The over/under is 48.

The Michigan Wolverines head into this game 5-2 this year. The last time they took the field, the Wolverines played the Washington Huskies and took home the win by a score of 24-7. The Michigan Wolverines ran the football 40 times and tallied 187 yds, which is an average of 4.7 yds per carry. In all, they tallied 68 plays which gave them a total of 417 yards. Michigan gave up 20 completions on 32 attempts for a total of 209 yds, and a completion percentage of 62.5%. When it came to the battle of the line of scrimmage, the Wolverines gave up 40 yards on 23 tries, which averages out to 1.7 yards per rush allowed.

When it comes to scoring points, the Michigan Wolverines have an average of 28.7 points per outing. Offensively they hold an average of 212.1 yards via the ground game giving them a rank of 22nd in Division 1. The Wolverines have earned 2,925 total yards over the course of this year. When it comes to scoring touchdowns, Michigan has totaled 7 touchdowns through the air and 18 rushing touchdowns. Michigan has recorded 142 1st downs, and they have committed 29 penalties for 263 yds. They have turned the football over 5 times.

Concerning passing yards, the Wolverines have conceded 1,506 yards which has them ranked 65th in the nation. They have allowed 215.1 yards per outing through the air as well as conceding a completion percentage of 66.5%. In total, they have relinquished 307.9 yards per outing putting them 24th in the nation. They have given up 8 touchdowns via the pass in addition to 6 touchdowns on the ground. They are allowing an average of 3.0 yards per rush on the ground and 92.7 rushing yards per game this year. Overall, they have conceded 649 running yards through 7 outings. The Wolverines rank 17th in Division 1 in terms of the opposition scoring, giving up 17.0 points per contest.

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The Spartans head into this game 3-4 for this season. When they last stepped on the field, the Spartans took a loss by a score of 38-13 against the Indiana Hoosiers. Michigan State ended up running for 3.1 yards per tote, finishing the contest with 74 yds on 24 carries. The Spartans ended up finishing with 367 yds while running 62 plays (5.9 yds per play). The Spartans pass defense allowed a completion percentage of 85.7%, relinquishing 332 yards on 24 out of 28 passing. Michigan State allowed 28 rushing attempts for 132 yds (4.7 yards per carry).

The Michigan State Spartans maintain an average of 336.7 yards per game, ranking them 108th in Division 1. The Michigan State offense has compiled 263 penalty yards on 32 infractions, which is 117th in the country in terms of hurting your team. They average 123.0 run yards per game and have rushed for 861 yards overall. They have given away 4 interceptions while conceding 4 fumbles and they have tallied 134 first downs. Regarding how much they score, the Spartans are 78th in college football with an average of 27.1 points per outing. During the season thus far, the Spartans currently have a total of 1,496 yards via the pass as well as an average of 213.7 passing yards per outing, putting them at 88th in the nation.

The Spartans are relinquishing 32.7 points per game, which puts them 121st in the country. Michigan State has given up a total of 919 yards via the ground game (131.3 yards/game) and 11 touchdowns via the rush so far this year. They have conceded 17 touchdowns through the air and 251.4 yards per game, which has them ranked 111th in the nation. The Spartans defense has participated in 432 plays, ranking them 36th in D-1. Their defense has earned 2 fumbles and 3 interceptions over the course of the season. In total, they have relinquished 229 points in total.

Who will win tonight's Wolverines/Spartans college football game against the spread?

Guy's Pick: Take the Spartans +14.0

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