Michigan Wolverines vs Northwestern Wildcats Prediction, 11/15/2025 College Football Picks, Best Bets & Odds

Game: Michigan Wolverines vs Northwestern Wildcats

Date: Saturday, November 15, 2025

Location: Wrigley Field in Chicago, IL

TV: FOX

Odds/Point Spread: Wildcats (+10.0)

Total/Over-Under: 40.5

Wrigley Field is the location where the Northwestern Wildcats (5-4) will try to beat the Michigan Wolverines (7-2) on Saturday, November 15, 2025. Michigan opens this contest as 10.0-point favorites. The over/under is 40.5.

The Michigan Wolverines step onto the field holding a record of 7-2 for this season. The last time they took the field, the Wolverines faced the Purdue Boilermakers and took home the win by a score of 21-16. When it came to stopping the run, the Wolverines conceded 138 yds on 39 tries, which averages out to 3.5 yards per run surrendered. Michigan gave up 20 completions on 26 attempts for 138 yards, and a completion rate of 76.9%. Once the final whistle blew, they ran 61 plays which totaled 398 yards. The Michigan Wolverines ended up rushing 39 times and recorded 253 yards, which had them averaging 6.5 yds per attempt.

The Wolverines have attained 3,685 yards in total this season. When it comes to getting the ball in the endzone, Michigan has totaled 7 touchdowns through the air and 25 touchdowns via the ground. They have turned the football over 8 different times. Michigan has recorded 182 first downs as an offense, and they have been hurt by 39 infractions for 356 yds. As a team they're averaging 223.8 yards in the run game giving them a rank of 12th in college football. Concerning putting points on the board, the Michigan Wolverines are averaging 28.1 points per game.

Regarding yards through the air, the Wolverines have given up 1,834 yards which has them ranked 60th in college football. They have conceded 203.8 yards per outing through the air as well as allowing a completion percentage of 66.3%. For the season, they are allowing 304.0 yards per game which has them sitting 18th in college football. They have granted 10 touchdowns via the pass in addition to 9 touchdowns via the ground game. Opposing teams are running for an average of 3.0 yards per running attempt and 100.2 rushing yards per game on the year. Overall, they have given up 902 running yards through 9 contests. The Wolverines are ranked 16th in the country regarding the opposition scoring, giving up 17.2 points per game.

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The Wildcats step onto the field holding a record of 5-4 for this year. The last time they took the gridiron, the Wildcats took a defeat with a final score of 38-17 when they faced the USC Trojans. Northwestern ran the football for 5.2 yards per tote, finishing with 130 yards on 25 attempts. The Wildcats finished with a total of 280 yds while running 55 plays (5.1 yards per play). The Wildcats passing defense conceded a completion percentage of 73.5%, relinquishing 309 yds on 25 for 34 through the air. Northwestern allowed 30 attempts on the ground for 173 yards (5.8 yards per carry).

In relation to putting points on the board, the Wildcats are ranked 111th in D-1 averaging 21.9 PPG. The Northwestern Wildcats average 351.3 yards/outing, which has them ranked 97th in D-1. The Northwestern offense has accrued 254 yards of penalties on 32 violations, which is 130th in D-1 in terms of helping out the other team. They have thrown 9 interceptions while allowing opponents to recover 6 fumbles and they have obtained 183 first downs. For the year thus far, the Wildcats have thrown for a total of 1,529 passing yards along with holding an average of 169.9 passing yards per game, which is ranked 119th in D-1. They hold an average of 181.4 rushing yards per game and have run for 1,633 yards overall.

Northwestern has surrendered a total of 1,285 yards rushing (142.8 yards per contest) in addition to 12 touchdowns on the ground this season. They have yielded 8 touchdowns from the passing game and 181.1 yards/contest, which has them sitting 20th in the country. Over the course of the season, they have given up 172 total points. They have totaled 4 fumbles and 6 picks so far this year. The Wildcats defense has been on the field for 522 plays, which ranks them 23rd in D-1. The Wildcats are conceding 19.1 PPG, ranking them 22nd in college football.

Who will win tonight's Wolverines/Wildcats college football game against the spread?

Josh's Pick: Take the Wildcats +10.0

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