Minnesota Golden Gophers vs Northwestern Wildcats Prediction, 11/22/2025 College Football Picks, Best Bets & Odds

Game: Minnesota Golden Gophers vs Northwestern Wildcats

Date: Saturday, November 22, 2025

Location: Wrigley Field in Chicago, IL

TV: BTN

Odds/Point Spread: Wildcats (-4.0)

Total/Over-Under: 40.5

Wrigley Field is the location where the Northwestern Wildcats (5-5) will go up against the Minnesota Golden Gophers (6-4) on Saturday, November 22, 2025. Northwestern opens as 4.0-point favorites from oddsmakers. The betting total is set at 40.5.

The Minnesota Golden Gophers head into this game 6-4 this year. In their last matchup, the Golden Gophers faced the Oregon Ducks and took a loss by a final of 42-13. For the game, they tallied 57 plays which gave them 200 yards. The Minnesota Golden Gophers ran the ball 24 different times and tallied 62 yards, which came out to an average of 2.6 yards per carry. In the running game, the Golden Gophers gave up 156 yds on 41 tries, which is 3.8 yds per rush surrendered. Minnesota gave up 20 completions on 28 tries for a total of 311 yards, and a completion rate of 71.4%.

In terms of scoring points, the Minnesota Golden Gophers hold an average of 22.7 points per outing. As a team they're averaging 105.0 yards on the ground which has them sitting 126th in the country. The Golden Gophers have racked up 3,018 yards in total for this campaign. In terms of getting in the endzone, Minnesota has amassed 12 touchdowns via the pass and 12 touchdowns via the ground. Minnesota has accounted for 178 1st downs as a team, and they have been flagged for 34 infractions for 283 yds. They have turned the ball over 8 times.

Concerning yards through the air, the Golden Gophers are giving up 2,162 yards which puts them in 61st in the nation. They have relinquished 216.2 yards per game through the air and allowed a completion percentage of 67.3%. During this campaign, they are giving up 331.4 yards per outing ranking them 38th in Division 1. They have conceded 13 touchdowns by air and 14 touchdowns pounding the rock. They are allowing an average of 3.6 yards per rush on the ground and 115.2 yards on the ground per contest for the season. During the season, they have allowed 1,152 yards on the ground through 10 contests. The Golden Gophers rank 63rd in the country when it comes to team defense, conceding 23.6 points per game.

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The Wildcats step onto the field holding a record of 5-5 for this season. For their last game, the Wildcats took a defeat with a final score of 24-22 against the Michigan Wolverines. Northwestern ran the ball for 2.3 yds per carry, finishing with 61 yds on 26 carries. The Wildcats finished the contest with a total of 245 yds while they ran 53 plays (4.6 yards per play). The Wildcats pass defense conceded a completion percentage of 73.5%, surrendering 309 yds on 25 out of 34 passing. Northwestern surrendered 30 rushing attempts for 173 yards (5.8 yds per carry).

The Northwestern Wildcats maintain an average of 340.7 yards per outing, which has them ranked 107th in Division 1. The Northwestern offense has compiled 309 penalty yards on 39 violations, which is good for 130th in the country in terms of giving up free yards. They have an average of 169.4 rushing yards per game and have run for 1,694 yards for the season. They have thrown 9 picks while surrendering 6 fumbles and they have been able to obtain 194 first downs. When it comes to how much they score, the Wildcats are ranked 109th in the country by scoring 21.9 PPG. During the season thus far, the Wildcats currently sit at 1,713 yards through the air as well as holding an average of 171.3 passing yards per game, ranking them 118th in college football.

The Wildcats are conceding 19.6 PPG, which has them sitting 23rd in the country. Northwestern has given up a total of 1,501 yards via the ground game (150.1 yards per contest) in addition to 15 touchdowns via the rush for the campaign. They have allowed the opposition 8 touchdowns through the air as well as 191.0 yards/game, which has them in 31st in the country. The Wildcats defense has taken part in 599 plays, which is 11th in Division 1. They have compiled 7 fumbles recovered and 8 interceptions so far this season. In total, they have relinquished 196 total points.

Who will win tonight's Golden Gophers/Wildcats college football game against the spread?

Tony's Pick: Take the Golden Gophers +4.0

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