North Texas Mean Green vs Charlotte 49ers Prediction, 10/24/2025 College Football Picks, Best Bets & Odds
Game: North Texas Mean Green vs Charlotte 49ers
Date: Friday, October 24, 2025
Location: Jerry Richardson Stadium in Charlotte, NC
TV: ESPN2
Odds/Point Spread: 49ers (+27.0)
Total/Over-Under: 61.5
Jerry Richardson Stadium is the site where the Charlotte 49ers (1-6) will go up against the North Texas Mean Green (6-1) on Friday, October 24, 2025. North Texas opens this contest as 27.0-point favorites from Vegas oddsmakers. The over/under is 61.5.
The North Texas Mean Green come into this matchup with a record of 6-1 for this season. The last time they stepped onto the field, the Mean Green faced the UTSA Roadrunners and went home with a win by a final score of 55-17. When it came to stopping the run, the Mean Green conceded 214 yards on 32 attempts, which averages out to 6.7 yards per rush surrendered. North Texas relinquished 15 pass completions on 25 attempts for 115 yards, and a completion percentage of 60.0%. Once the final whistle blew, they ran 81 plays which converted into 584 yds. The North Texas Mean Green ran the ball a total of 44 times and tallied 270 yds, which had them averaging 6.1 yards per attempt.

The Mean Green have earned 3,212 total yards for the year. When it comes to distribution of touchdowns, North Texas has compiled 18 touchdowns via the pass and 23 rushing touchdowns. They have surrendered the ball 8 different times. North Texas has accounted for 182 1st downs, and they have been called for 41 penalties for 337 yds. As a team they're maintaining an average of 182.7 yards on the ground which has them sitting 45th in college football. In terms of putting the ball in the endzone, the North Texas Mean Green have an average of 45.0 points per contest.
The Mean Green are ranked 80th in D-1 regarding the opposition scoring, conceding 25.7 PPG. They are allowing an average of 4.5 yards per running attempt and 203.1 rushing yards per game on the season. During this campaign, they have given up 1,422 rushing yards through 7 games. When it comes to passing yardage, the Mean Green are giving up 1,068 yds which puts them in 10th in the nation. They are giving up 152.6 yards per contest via the pass in addition to allowing a completion percentage of 58.6%. In total, they have surrendered 355.7 yards per outing putting them at 58th in college football. They have yielded 9 touchdowns via the pass in addition to 13 touchdowns pounding the rock.
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The 49ers head into this game 1-6 for this season. When they last stepped on the gridiron, the 49ers took a defeat with a final score of 49-14 when they played the Temple Owls. Charlotte gave up 30 run attempts for 172 yds (5.7 yds per rush). The 49ers secondary gave up a completion percentage of 69.6%, relinquishing 212 yds on 16 out of 23 passing. The 49ers finished the game with a total of 357 yds and they ran 76 plays (4.7 yards per play). Charlotte ran for 4.2 yards per carry, finishing the game with 199 yards on 47 carries.
The Charlotte 49ers maintain an average of 314.3 yards per game, which is good for 121st in college football. The Charlotte offense has racked up 364 penalty yds on 44 infractions, which ranks them 62nd in the country in terms of giving up free yards. They are averaging 107.1 run yards per game and have run for 750 yards for this year. They have given away 7 picks while letting opponents recover 9 fumbles and they have recorded 134 1st downs. Regarding putting points on the board, the 49ers rank 128th in Division 1 averaging 17.1 PPG. For the year thus far, the 49ers have racked up 1,450 yards through the air along with holding an average of 207.1 throwing yards per contest, which is ranked 94th in Division 1.
Charlotte has allowed a total of 1,516 rushing yards (216.6 yards per game) and 14 touchdowns on the ground so far this year. They have conceded 16 touchdowns via the pass and 221.9 yards per outing, ranking them 70th in D-1. Over the course of the season, they have given up 244 points in total. They have tallied 4 fumbles recovered and 2 interceptions on the season. The 49ers defense has taken part in 496 plays, which ranks 112th in college football. The 49ers are relinquishing 34.9 points per contest, which has them sitting 127th in the nation.
Who will win tonight's Mean Green/49ers college football game against the spread?
Parlays Pundit's Pick: Take the 49ers +27.0
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Additional Resources:
Charlotte 49ers - Twitter
North Texas Mean Green - Twitter