Ohio Bobcats vs Buffalo Bulls Prediction, 11/28/2025 College Football Picks, Best Bets & Odds

Game: Ohio Bobcats vs Buffalo Bulls

Date: Friday, November 28, 2025

Location: UB Stadium in Buffalo, NY

TV: ESPNU

Odds/Point Spread: Bulls (+7.0)

Total/Over-Under: 44.5

UB Stadium is the location where the Buffalo Bulls (5-6) will go up against the Ohio Bobcats (7-4) on Friday, November 28, 2025. Buffalo opens this game as 7.0-point dogs from Vegas oddsmakers. The betting total comes in at 44.5.

The Ohio Bobcats head into this game 7-4 this season. The last time they stepped onto the field, the Bobcats played against the UMass Minutemen and went home with a win by a final score of 42-14. The Ohio Bobcats ran the rock 57 different times and accounted for 363 yds, which is an average of 6.4 yards per tote. For the game, they had 65 plays which totaled 391 yds. Ohio allowed 15 pass completions on 28 tries for 90 yds, and a completion rate of 53.6%. Against the run, the Bobcats gave up 125 yds on 39 attempts, which is an average of 3.2 yards per run surrendered.

When it comes to scoring points, the Ohio Bobcats are averaging 28.5 PPG. As a unit they are averaging 216.9 yards on the ground giving them a rank of 15th in Division 1. The Bobcats have racked up 4,490 total yards for the year. With reference to distribution of touchdowns, Ohio has compiled 12 passing touchdowns and 28 rushing touchdowns. Ohio has accounted for 235 1st downs as an offense, and they have been called for 70 infractions for 538 yards. They have given the ball to the opposition 14 times.

When talking about passing yardage, the Bobcats are giving up 2,251 yards which ranks them 47th in D-1. They have relinquished 204.6 yards per game via the pass in addition to giving up a completion percentage of 64.7%. In total, they have relinquished 356.9 yards per contest which has them ranked 58th in D-1. They have conceded 17 touchdowns by air as well as 12 touchdowns running the ball. They are allowing teams to run for an average of 4.6 yards per rushing attempt and 152.3 yards on the ground per game this season. During this campaign, they have given up 1,675 rushing yards through 11 contests. The Bobcats are ranked 50th in the country regarding the opposition scoring, giving up 22.6 PPG.

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The Bulls step onto the field holding a record of 5-6 for this season. In their last game, the Bulls went home defeated by a final of 37-20 when they played the Miami RedHawks. The Bulls finished the game with a total of 349 yards while running 82 plays (4.3 yds per play). Buffalo ran the ball for 1.4 yds per carry, finishing the contest with 46 yards on 33 attempts. Buffalo surrendered 41 run attempts for 162 yds (4.0 yards per rush). The Bulls pass defense gave up a completion percentage of 52.0%, relinquishing 185 yds on 13 out of 25 through the air.

In relation to their ability to score points, the Bulls sit 95th in college football with 23.8 points per game. The Buffalo Bulls are averaging 360.0 yards/outing, which ranks them 88th in the country. The Buffalo offense has compiled 503 yds of penalties on 61 infractions, which ranks 95th in the nation in terms of giving up free yards. They have given away 13 picks while surrendering 8 fumbles and they have been able to earn 213 1st downs. Over the course of the season thus far, the Bulls have compiled 2,478 yards through the air along with an average of 225.3 passing yards per game, ranking them 71st in D-1. They have an average of 134.7 yards via the ground game and have run for 1,482 yards for this season.

The Bulls are surrendering 22.8 points per game, which puts them 51st in college football. Buffalo has conceded a total of 1,527 yards via the ground game (138.8 yards per contest) and 14 touchdowns via the rush for the season. They have allowed 15 touchdowns via the pass as well as 190.0 yards per game, which has them in 26th in Division 1. The Bulls defense has taken part in 767 plays, which has them ranked 105th in Division 1. Their defense has 6 fumbles and 6 picks over the course of the season. Overall, they have relinquished 251 pts.

Who will win tonight's Bobcats/Bulls college football game against the spread?

Tony's Pick: Take the Bobcats -7.0

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