Ohio State Buckeyes vs Washington Huskies Prediction, 9/27/2025 College Football Picks, Best Bets & Odds

Game: Ohio State Buckeyes vs Washington Huskies

Date: Saturday, September 27, 2025

Location: Husky Stadium in Seattle, WA

TV: CBS

Odds/Point Spread: Huskies (+8.0)

Total/Over-Under: 52.5

Husky Stadium is where the Washington Huskies (3-0) will take on the Ohio State Buckeyes (3-0) on Saturday, September 27, 2025. Ohio State opens this contest as 8.0-point favorites from Vegas oddsmakers. The betting total is set at 52.5.

The Ohio State Buckeyes come into this game with a record of 3-0 for this year. In their last matchup, the Buckeyes played against the Ohio Bobcats and walked away with a win by a score of 37-9. Once the final whistle blew, they ran 63 plays which gave them a total of 572 yds. The Ohio State Buckeyes ran the rock 31 different times and recorded 225 yds, which earned them an average of 7.3 yds per carry. Against the run, the Buckeyes gave up 68 yds on 34 attempts, which averages out to 2.0 yds per run allowed. Ohio State relinquished 10 pass completions on 21 tries for a total of 113 yards, and a completion rate of 47.6%.

In terms of putting the ball in the endzone, the Ohio State Buckeyes are averaging 40.3 PPG. As a team they average 192.0 yards on the ground which has them sitting 46th in Division 1. The Buckeyes have attained 1,426 total yards this season. In terms of scoring touchdowns, Ohio State has amassed 9 touchdowns via the pass and 6 touchdowns via the ground. Ohio State has 71 1st downs, and they have been called for 11 penalties for 80 yds. They have surrendered the ball 3 times.

When talking about passing yardage, the Buckeyes are conceding 355 yards which ranks them 6th in the nation. They have conceded 118.3 yards per contest via the pass and allowed a completion percentage of 52.3%. For the season, they are allowing 227.7 yards per contest putting them at 11th in D-1. They have granted 2 touchdowns through the air and 0 touchdowns on the ground. They are allowing teams to run for an average of 3.2 yards per tote and 109.3 rushing yards per contest this year. Overall, they have allowed 328 yards via the ground game in 3 contests. The Buckeyes are sitting in 1st in D-1 when it comes to team defense, allowing 5.3 PPG.

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The Huskies come into this game with a record of 3-0 this year. The last time they took the field, the Huskies took home the win by a final score of 59-24 against the Washington State Cougars. The Huskies finished the contest with a total of 471 yards and they ran 52 plays (9.1 yards per play). Washington rushed for 5.2 yards per attempt, finishing the contest with 173 yards on 33 carries. Washington allowed 28 attempts on the ground for 27 yards (1.0 yards per rush). The Huskies passing defense conceded a completion percentage of 69.4%, relinquishing 277 yards on 25 for 36 through the air.

Regarding how much they score, the Huskies sit 2nd in the country maintaining an average of 55.7 PPG. The Washington Huskies hold an average of 536.0 yards/game, which has them ranked 10th in the country. The Washington offense has 149 yds of penalties on 16 violations, which has them sitting 112th in Division 1 in terms of hurting your team. They have tossed 0 picks while surrendering 1 fumble and they have been able to earn 83 1st downs. For the season thus far, the Huskies have thrown for a total of 828 passing yards along with an average of 276.0 passing yards per game, giving them a rank of 30th in D-1. They average 260.0 yards per game via the ground game and have rushed for 780 yards for the season.

Washington has allowed the opposition a total of 188 yards via the ground game (62.7 yards per outing) as well as 3 touchdowns via the rush on the year. They have surrendered 4 touchdowns through the air as well as 199.7 yards per outing, which has them ranked 62nd in the country. Overall, they have conceded 55 total points. Their defense has tallied 1 fumble recovered and 4 picks over the course of the season. The Huskies defense has participated in 176 plays, which has them ranked 7th in D-1. The Huskies are relinquishing 18.3 PPG, which has them ranked 41st in the country.

Who will win tonight's Buckeyes/Huskies college football game against the spread?

Guy's Pick: Take the Buckeyes -8.0

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