Oklahoma State Cowboys vs UCF Knights Prediction, 11/22/2025 College Football Picks, Best Bets & Odds
Game: Oklahoma State Cowboys vs UCF Knights
Date: Saturday, November 22, 2025
Location: FBC Mortgage Stadium in Orlando, FL
TV: ESPN+
Odds/Point Spread: Knights (-14.0)
Total/Over-Under: 48
The UCF Knights (4-6) will compete against the Oklahoma State Cowboys (1-9) at FBC Mortgage Stadium on Saturday, November 22, 2025. UCF is 14.0-point favorites from oddsmakers. The total comes in at 48.
The Oklahoma State Cowboys head into this game 1-9 for this season. In their last game, the Cowboys took the field against the Kansas State Wildcats and went home with a loss by a final score of 14-6. The Oklahoma State Cowboys rushed the ball a total of 29 times and accounted for 147 yards, which is an average of 5.1 yds per attempt. In all, they ran 67 plays for 373 yards. Oklahoma State allowed 13 pass completions on 19 attempts for a total of 110 yards, and a completion rate of 68.4%. In the running game, the Cowboys conceded 232 yds on 39 tries, which is 5.9 yards per rush allowed.

The Cowboys have earned 3,052 total yards this season. When it comes to getting in the endzone, Oklahoma State has amassed 6 touchdowns through the air and 8 rushing touchdowns. They have turned the football over 14 times. Oklahoma State has accounted for 164 1st downs, and they have been called for 58 penalties for 513 yds. As a team they have an average of 128.9 yards on the ground which ranks them 101st in the nation. When it comes to scoring, the Oklahoma State Cowboys are averaging 14.3 points per outing.
When it comes to yards via the pass, the Cowboys have allowed 2,645 yds which puts them in 119th in the nation. They have relinquished 264.5 yards per outing via the pass in addition to allowing a completion percentage of 66.9%. Overall, they have relinquished 427.8 yards per game which has them sitting 124th in Division 1. They have relinquished 25 touchdowns via the pass and 17 touchdowns on the ground. They are allowing teams to run for an average of 4.4 yards per rush on the ground and 163.3 rushing yards per game so far this year. Over the course of this year, they have allowed 1,633 yards via the ground game in 10 contests. The Cowboys are sitting in 131st in Division 1 regarding team defense, giving up 36.3 points per contest.
Get all of our College Football Picks this Week
The Knights step onto the field holding a record of 4-6 for this season. In their last game, the Knights went home defeated by a final of 48-9 when they faced the Texas Tech Red Raiders. The Knights ended up finishing with 230 yards while running 62 plays (3.7 yards per play). UCF ran for 1.8 yards per carry, finishing with 52 yards on 29 carries. UCF gave up 35 rushing attempts for 205 yards (5.9 yds per rush). The Knights pass defense conceded a completion percentage of 75.0%, relinquishing 294 yds on 27 for 36 passing.
Regarding their scoring prowess, the Knights are ranked 82nd in college football maintaining an average of 25.4 points per game. The UCF Knights are averaging 385.3 yards per game, ranking them 72nd in D-1. The UCF offense has 580 yds of penalties on 75 infractions, which ranks 18th in the country in terms of hurting your team. They have thrown 9 interceptions while surrendering 5 fumbles and they have been able to earn 187 1st downs. For the year so far, the Knights currently sit at 2,124 passing yards as well as an average of 212.4 passing yards per game, ranking them 88th in the nation. They have an average of 172.9 run yards per game and have rushed for 1,729 yards for the season.
UCF has given up a total of 1,586 yards on the ground (158.6 yards per contest) and 14 touchdowns by way of the ground game on the season. They have given up 11 touchdowns via the pass in addition to 180.8 yards per outing, which puts them in 21st in the nation. This year, they have allowed 228 total points. Their defense has tallied 5 fumbles recovered and 8 interceptions on the season. The Knights defense has taken the field for 672 plays, which is good for 77th in Division 1. The Knights are surrendering 22.8 PPG, ranking them 52nd in D-1.
Who will win tonight's Cowboys/Knights college football game against the spread?
Guy's Pick: Take the Cowboys +14.0
Get $60 worth of FREE premium member picks. No Obligation. No Salesman. No Credit Card. Fast Sign up with Instant Access Click Here
Get college football picks on every single game, or if you want our very best bets by the experts, sign up for your free $60 account with a guarantee.
Get all of this Weeks Free College Football Picks
Get all of this Weeks Expert College Football Picks
Additional Resources:
UCF Knights - Twitter
Oklahoma State Cowboys - Twitter

