Ole Miss Rebels vs Oklahoma Sooners Prediction, 10/25/2025 College Football Picks, Best Bets & Odds

Game: Ole Miss Rebels vs Oklahoma Sooners

Date: Saturday, October 25, 2025

Location: Memorial Stadium in Norman, OK

TV: ABC

Odds/Point Spread: Sooners (-5.0)

Total/Over-Under: 54

Memorial Stadium is the site where the Oklahoma Sooners (6-1) will go up against the Ole Miss Rebels (6-1) on Saturday, October 25, 2025. Ole Miss opens this game as 5.0-point underdogs. The total is set at 54.

The Ole Miss Rebels head into this game 6-1 this season. In their last contest, the Rebels faced the Georgia Bulldogs and took a loss by a score of 43-35. In the running game, the Rebels gave up 221 yards on 49 attempts, which is an average of 4.5 yds per run allowed. Ole Miss relinquished 26 pass completions on 31 attempts for 289 yards, and a completion rate of 83.9%. On the day, they had 60 plays which gave them 351 yds. The Ole Miss Rebels ended up running the ball 24 different times and totaled 88 yds, which came out to an average of 3.7 yards per carry.

The Rebels currently have 3,443 yards in total this season. In terms of getting in the endzone, Ole Miss has earned 12 passing touchdowns and 20 rushing touchdowns. They have turned the ball over 8 times. Ole Miss has recorded 176 first downs as a team, and they have been called for 51 infractions for 483 yds. As a unit they're averaging 187.7 yards via the ground game which ranks them 41st in the country. When talking about putting points on the board, the Ole Miss Rebels have an average of 37.4 points per outing.

Concerning passing yards, the Rebels are giving up 1,369 yards which ranks them 41st in Division 1. They have yielded 195.6 yards per outing through the air in addition to giving up a completion percentage of 60.1%. For the year, they have yielded 362.3 yards/outing which ranks them 66th in D-1. They have given up 10 touchdowns via the pass in addition to 9 touchdowns running the ball. They are giving up 4.7 yards per rush and 166.7 yards on the ground per game this season. Overall, they have conceded 1,167 rushing yards through 7 games. The Rebels rank 53rd in D-1 in terms of team defense, giving up 22.6 points per game.

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The Sooners head into this game 6-1 this season. The last time they took the field, the Sooners went home victorious with a score of 26-7 against the South Carolina Gamecocks. The Sooners finished the game with a total of 319 yds and they ran 67 plays (4.8 yards per play). Oklahoma ran for 4.3 yards per tote, totaling 171 yds on 40 attempts. Oklahoma gave up 34 running attempts for 54 yards (1.6 yds per rush). The Sooners pass defense conceded a completion percentage of 63.6%, surrendering 170 yds on 21 out of 33 passing.

Concerning their scoring prowess, the Sooners rank 70th in Division 1 holding an average of 28.7 points per outing. The Oklahoma Sooners average 379.0 yards/game, which has them ranked 74th in Division 1. The Oklahoma offense has totaled 412 penalty yards on 44 infractions, which is 61st in Division 1 in terms of hurting your team. They have tossed 6 picks while allowing opponents to recover 3 fumbles and they have earned 149 first downs. During the season thus far, the Sooners have compiled 1,748 passing yards as well as an average of 249.7 throwing yards per outing, ranking them 52nd in college football. They hold an average of 129.3 yards per game via the rush and have run for 905 yards for the season.

The Sooners are conceding 9.4 points per contest, which has them sitting 2nd in D-1. Oklahoma has surrendered a total of 563 yards on the ground (80.4 yards per game) and 2 touchdowns on the ground so far this season. They have given up 3 touchdowns through the air in addition to 132.6 yards per game, which has them sitting 4th in college football. The Sooners defense has taken part in 405 plays, which has them sitting 16th in the nation. They have tallied 1 fumble recovered and 3 interceptions on the season. Over the course of the season, they have allowed 66 points in total.

Who will win tonight's Rebels/Sooners college football game against the spread?

Guy's Pick: Take the Rebels +5.0

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