Oregon Ducks vs Northwestern Wildcats Prediction, 9/13/2025 College Football Picks, Best Bets & Odds

Game: Oregon Ducks vs Northwestern Wildcats

Date: Saturday, September 13, 2025

Location: Martin Stadium in Evanston, IL

TV: FOX

Odds/Point Spread: Wildcats (+27.5)

Total/Over-Under: 51

Martin Stadium is where the Northwestern Wildcats (1-1) will go up against the Oregon Ducks (2-0) on Saturday, September 13, 2025. Northwestern opens this contest as 27.5-point dogs. The total is set at 51.

The Oregon Ducks step onto the field holding a record of 2-0 for this season. In their last matchup, the Ducks played the Oklahoma State Cowboys and walked away with a win by a score of 69-3. Against the run, the Ducks gave up 144 yds on 42 tries, which is an average of 3.4 yds per run allowed. Oregon relinquished 7 completions on 19 attempts for 67 yds, and a completion percentage of 36.8%. When all was said and done, they ran 62 plays for 631 yds. The Oregon Ducks ran the football 37 different times and had 312 yds, earning them an average of 8.4 yards per attempt.

The Ducks have earned 1,137 total yards this year. In terms of getting in the endzone, Oregon has compiled 6 passing touchdowns and 10 touchdowns on the ground. They have yet to turn the ball over. Oregon has earned 53 1st downs as an offense, and they have been called for 9 penalties for 64 yds. As a team they're holding an average of 282.5 yards via the ground game ranking them 6th in Division 1. Regarding putting points on the board, the Oregon Ducks are averaging 64.0 points per outing.

The Ducks rank 12th in the nation concerning team defense, conceding 8.0 PPG. They are allowing 2.8 yards per run and 95.0 rushing yards per game so far this season. Overall, they have conceded 190 rushing yards through 2 games. When talking about yards through the air, the Ducks have conceded 265 yds which ranks them 23rd in college football. They have yielded 132.5 yards per contest via the pass as well as giving up a completion percentage of 60.0%. Over the course of this year, they are surrendering 227.5 yards per game which has them sitting 22nd in the country. They have conceded 1 touchdown via the ground game.

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The Wildcats come into this matchup with a record of 1-1 for this season. The last time they took the field, the Wildcats walked away with a victory by a final of 42-7 when they played the Western Illinois Leathernecks. Northwestern rushed the ball for 6.9 yards per attempt, finishing with a total of 281 yds on 41 carries. The Wildcats finished the game with 526 yards and they ran 70 plays (7.5 yds per play). The Wildcats pass defense allowed a completion rate of 44.4%, relinquishing 110 yards on 12 for 27 through the air. Northwestern conceded 23 rush attempts for 71 yds (3.1 yds per rush).

In relation to their ability to score points, the Wildcats currently sit 98th in college football holding an average of 22.5 points per contest. The Northwestern Wildcats average 381.5 yards per game, which is good for 76th in Division 1. The Northwestern offense has totaled 73 penalty yards on 10 violations, which is good for 90th in the country in terms of helping out the opposition. They have thrown 4 picks while losing 2 fumbles and they have obtained 43 first downs. During the season thus far, the Wildcats currently sit at 406 yards through the air in addition to holding an average of 203.0 passing yards per game, giving them a rank of 83rd in the country. They average 178.5 run yards per game and have toted the ball for 357 yards in total.

Northwestern has conceded a total of 340 rushing yards (170.0 yards/game) and 1 touchdown via the rush on the season. They have surrendered 2 touchdowns through the air in addition to 131.0 yards/outing, which has them ranked 19th in the nation. Their defense has totaled 0 fumbles recovered and 1 interception this year. The Wildcats defense has taken the field for 124 plays, which ranks 51st in the nation. The Wildcats are conceding 15.0 points per game, which puts them 49th in college football.

Who will win tonight's Ducks/Wildcats college football game against the spread?

Josh's Pick: Take the Ducks -27.5

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