Penn State Nittany Lions vs UCLA Bruins Prediction, 10/4/2025 College Football Picks, Best Bets & Odds

Game: Penn State Nittany Lions vs UCLA Bruins

Date: Saturday, October 4, 2025

Location: Rose Bowl in Pasadena, CA

TV: CBS

Odds/Point Spread: Bruins (+24.5)

Total/Over-Under: 50

The UCLA Bruins (0-4) are hosting the Penn State Nittany Lions (3-1) at Rose Bowl on Saturday, October 4, 2025. UCLA opens this game as 24.5-point dogs from oddsmakers. The betting total comes in at 50.

The Penn State Nittany Lions come into this game with a record of 3-1 for this season. In their last contest, the Nittany Lions stepped onto the field against the Oregon Ducks and walked away from this one with a loss by a score of 30-24. Against the run, the Nittany Lions gave up 176 yds on 39 tries, which averages out to 4.5 yards per run allowed. Penn State conceded 29 pass completions on 39 tries for 248 yards, and a completion percentage of 74.4%. On the day, they tallied 60 plays which converted into 276 yds. The Penn State Nittany Lions ended up running the ball 35 different times and had 139 yards, which earned them an average of 4.0 yards per tote.

Regarding getting in the endzone, the Penn State Nittany Lions are averaging 39.0 points per outing. As a unit they're averaging 180.0 yards on the ground ranking them 53rd in college football. The Nittany Lions have earned 1,588 total yards this year. When it comes to getting the ball in the endzone, Penn State has amassed 7 touchdowns through the air and 10 touchdowns on the ground. Penn State has earned 88 first downs as a team, and they have committed 13 infractions for 90 yards. They have surrendered the ball 2 different times.

Concerning passing yardage, the Nittany Lions have given up 618 yds which has them ranked 13th in the country. They have conceded 154.5 yards per outing via the pass and allowed a completion percentage of 59.3%. In total, they are surrendering 274.0 yards/contest which puts them 19th in the country. They have conceded 5 touchdowns via the pass as well as 1 touchdown on the ground. They are allowing an average of 3.3 yards per rush and 119.5 yards on the ground per game for the season. Over the course of this season, they have allowed 478 rushing yards through 4 games. The Nittany Lions rank 10th in college football regarding team defense, conceding 11.8 PPG.

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The Bruins step onto the field holding a record of 0-4 for this season. The last time they took the field, the Bruins walked away with a loss by a score of 17-14 when they played the Northwestern Wildcats. UCLA relinquished 42 run attempts for 199 yds (4.7 yards per rush). The Bruins pass defense gave up a completion rate of 66.7%, relinquishing 115 yds on 12 out of 18 through the air. The Bruins finished the game with 311 yards while running 57 plays (5.5 yards per play). UCLA rushed the ball for 4.5 yards per carry, finishing the contest with 131 yds on 29 carries.

The UCLA Bruins hold an average of 321.3 yards per game, which is good for 119th in college football. The UCLA offense has totaled 335 penalty yards on 36 violations, which ranks 23rd in the nation in terms of hurting your team. They have an average of 124.3 run yards per game and have toted the ball for 497 yards for this season. They have thrown 3 interceptions while letting opponents recover 1 fumble and they have been able to obtain 74 1st downs. Regarding the points being put on the board, the Bruins currently rank 134th in the country by tallying 14.3 points per game. For the year thus far, the Bruins currently sit at 788 passing yards as well as holding an average of 197.0 throwing yards per outing, which has them ranked 99th in college football.

The Bruins are conceding 31.3 PPG, which has them ranked 119th in the nation. UCLA has allowed a total of 931 rushing yards (232.8 yards/game) as well as 9 touchdowns on the ground this year. They have allowed 8 touchdowns from the passing game and 169.0 yards/outing, which has them ranked 26th in college football. The Bruins defense has participated in 256 plays, which has them ranked 28th in the nation. Their defense has 2 fumbles and no picks this season. This season, they have relinquished 125 points in total.

Who will win tonight's Nittany Lions/Bruins college football game against the spread?

Tony's Pick: Take the Nittany Lions -24.5

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