Purdue Boilermakers vs Michigan Wolverines Prediction, 11/1/2025 College Football Picks, Best Bets & Odds

Game: Purdue Boilermakers vs Michigan Wolverines

Date: Saturday, November 1, 2025

Location: Michigan Stadium in Ann Arbor, MI

TV: BTN

Odds/Point Spread: Wolverines (-21.0)

Total/Over-Under: 51.5

Michigan Stadium is the location where the Michigan Wolverines (5-2) will take on the Purdue Boilermakers (2-6) on Saturday, November 1, 2025. Purdue opens this game as 21.0-point dogs from oddsmakers. The over/under is set at 51.5.

The Purdue Boilermakers head into this matchup 2-6 for this season. In their last matchup, the Boilermakers stepped onto the field against the Rutgers Scarlet Knights and ended up losing by a score of 27-24. In all, they ran 51 plays which converted into 345 yds. The Purdue Boilermakers ended up rushing 28 times and tallied 217 yds, which earned them an average of 7.8 yards per attempt. Against the run, the Boilermakers conceded 184 yds on 48 attempts, which averages out to 3.8 yards per rush surrendered. Purdue conceded 19 completions on 27 attempts for a total of 359 yds, and a completion percentage of 70.4%.

When it comes to putting points on the board, the Purdue Boilermakers are averaging 22.9 PPG. As a team they maintain an average of 141.6 yards in the run game ranking this team at 86th in Division 1. The Boilermakers have attained 3,102 total yards for this campaign. When it comes to scoring touchdowns, Purdue has compiled 12 touchdowns through the air and 10 rushing touchdowns. Purdue has tallied 170 first downs as an offense, and they have been called for 42 infractions for 420 yards. They have surrendered the ball 16 times.

The Boilermakers are ranked 92nd in college football when it comes to the opposition scoring, giving up 27.8 points per game. They are allowing an average of 3.9 yards per rush and 149.0 rushing yards per game for the season. Overall, they have conceded 1,192 rushing yards through 8 outings. In terms of passing yards, the Boilermakers have given up 1,965 yds which has them sitting in 115th in the nation. They are conceding 245.6 yards per contest via the pass and giving up a completion percentage of 61.5%. In total, they have relinquished 394.6 yards per contest ranking them 97th in Division 1. They have yielded 9 touchdowns by air as well as 13 touchdowns pounding the rock.

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The Wolverines head into this game 5-2 for this season. The last time they took the field, the Wolverines took home the win by a final score of 31-20 when they played the Michigan State Spartans. The Wolverines finished with 362 yds while running 66 plays (5.5 yards per play). Michigan rushed for 5.6 yards per tote, totaling 276 yds on 49 attempts. Michigan relinquished 38 rush attempts for 115 yds (3.0 yards per carry). The Wolverines pass defense allowed a completion percentage of 55.9%, surrendering 190 yds on 19 for 34 passing.

The Michigan Wolverines have an average of 410.9 yards per game, which has them sitting 53rd in college football. The Michigan offense has racked up 324 penalty yds on 35 violations, which is 120th in the nation in terms of making mistakes. They average 220.1 yards per game on the ground and have rushed for 1,761 yards overall. They have tossed 3 interceptions while losing 3 fumbles and they have tallied 162 1st downs. In relation to how much they score, the Wolverines rank 69th in the country scoring 29.0 points per game. For the season so far, the Wolverines have racked up 1,526 yards through the air in addition to holding an average of 190.8 passing yards per outing, giving them a rank of 103rd in college football.

The Wolverines are conceding 17.4 PPG, which has them ranked 19th in D-1. Michigan has yielded a total of 764 yards via the ground game (95.5 yards per game) and 8 touchdowns by way of the ground game for the year. They have allowed 9 touchdowns from the passing game and 212.0 yards/game, which has them ranked 55th in the country. The Wolverines defense has participated in 527 plays, which is good for 85th in Division 1. They have totaled 4 fumbles recovered and 11 interceptions so far this year. In total, they have conceded 139 pts.

Who will win tonight's Boilermakers/Wolverines college football game against the spread?

Tony's Pick: Take the Wolverines -21.0

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