SMU Mustangs vs Wake Forest Demon Deacons Prediction, 10/25/2025 College Football Picks, Best Bets & Odds
Game: SMU Mustangs vs Wake Forest Demon Deacons
Date: Saturday, October 25, 2025
Location: Allegacy Federal Credit Union Stadium in Winston-Salem, NC
TV: The CW Network
Odds/Point Spread: Demon Deacons (+3.5)
Total/Over-Under: 54
Allegacy Federal Credit Union Stadium is where the Wake Forest Demon Deacons (4-2) will compete against the SMU Mustangs (5-2) on Saturday, October 25, 2025. Wake Forest opens this matchup as 3.5-point dogs from oddsmakers. The betting total comes in at 54.
The SMU Mustangs step onto the field holding a record of 5-2 this year. The last time they took the field, the Mustangs faced off with the Clemson Tigers and went home with a win by a final score of 35-24. The SMU Mustangs ran the ball a total of 28 different times and had 139 yards, earning them an average of 5.0 yards per carry. Once the final whistle blew, they tallied 71 plays for 429 yards. SMU gave up 29 completions on 42 tries for a total of 317 yds, and a completion rate of 69.0%. Against the run, the Mustangs gave up 35 yds on 30 tries, which is an average of 1.2 yds per run allowed.

The Mustangs currently have 2,858 yards in total this season. When it comes to getting in the endzone, SMU has earned 17 passing touchdowns and 11 rushing touchdowns. They have turned the ball over 10 different times. SMU has compiled 150 1st downs as a unit, and they have committed 47 infractions for 467 yds. Offensively they average 128.7 yards on the ground ranking this team at 100th in college football. When talking about getting in the endzone, the SMU Mustangs have an average of 34.1 points per outing.
In terms of yards through the air, the Mustangs have conceded 2,212 yds which puts them in 136th in the nation. They have relinquished 316.0 yards per outing through the air and giving up a completion percentage of 57.6%. Overall, they have given up 413.0 yards per outing which ranks them 114th in Division 1. They have granted 15 touchdowns via the pass in addition to 4 touchdowns via the ground game. Opposing teams are running for an average of 2.8 yards per run and 97.0 yards on the ground per game on the year. Overall, they have given up 679 rushing yards through 7 outings. The Mustangs are ranked 55th in college football when it comes to their opponents scoring, giving up 22.6 PPG.
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The Demon Deacons head into this matchup 4-2 for this season. When they last played, the Demon Deacons walked away with a victory by a final of 39-14 when they faced the Oregon State Beavers. The Demon Deacons finished the contest with a total of 468 yds while running 54 plays (8.7 yds per play). Wake Forest rushed the ball for 7.6 yards per tote, finishing the game with 198 yds on 26 attempts. Wake Forest surrendered 38 running attempts for 134 yards (3.5 yds per rush). The Demon Deacons pass defense allowed a completion percentage of 45.2%, surrendering 175 yds on 19 out of 42 passing.
In terms of their scoring prowess, the Demon Deacons are 68th in college football holding an average of 29.0 PPG. The Wake Forest Demon Deacons are averaging 409.8 yards per outing, which is good for 54th in college football. The Wake Forest offense has compiled 454 yds of penalties on 50 infractions, which ranks them 28th in college football in terms of helping out the opposition. They have tossed 4 interceptions while letting opponents recover 2 fumbles and they have been able to earn 109 first downs. For the season so far, the Demon Deacons currently have a total of 1,498 yards via the pass as well as holding an average of 249.7 passing yards per outing, giving them a rank of 53rd in D-1. They are averaging 160.2 yards per game via the ground game and have rushed for 961 yards for the season.
The Demon Deacons are surrendering 20.0 points per game, which has them ranked 36th in the nation. Wake Forest has given up a total of 846 yards rushing (141.0 yards/game) as well as 6 touchdowns via the rush this season. They have conceded 6 touchdowns through the air and 181.3 yards per game, which has them ranked 27th in the country. The Demon Deacons defense has participated in 456 plays, which ranks them 60th in D-1. Their defense has earned 3 fumbles recovered and 3 interceptions for the season. This year, they have allowed 120 total points.
Who will win tonight's Mustangs/Demon Deacons college football game against the spread?
Josh's Pick: Take the Mustangs -3.5
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Additional Resources:
Wake Forest Demon Deacons - Twitter
SMU Mustangs - Twitter