Stanford Cardinal vs BYU Cougars Prediction, 9/6/2025 College Football Picks, Best Bets & Odds

Game: Stanford Cardinal vs BYU Cougars

Date: Saturday, September 6, 2025

Location: LaVell Edwards Stadium in Provo, UT

TV: ESPN/ESPN+

Odds/Point Spread: Cougars (-18.5)

Total/Over-Under: 46.5

The Stanford Cardinal (0-1) are hitting the road to LaVell Edwards Stadium on Saturday, September 6, 2025 where they will attempt to beat the BYU Cougars (1-0). BYU opens this game as 18.5-point favorites. The over/under comes in at 46.5.

The Stanford Cardinal head into this matchup 0-1 for this season. The last time they stepped onto the field, the Cardinal stepped onto the field against the Hawaii Warriors and ended up losing by a score of 23-20. When it came to stopping the run, the Cardinal conceded 96 yards on 24 tries, which averages out to 4.0 yards per run surrendered. Stanford allowed 27 completions on 40 attempts for 210 yards, and a completion percentage of 67.5%. In all, they tallied 73 plays for 286 yards. The Stanford Cardinal ended up running the ball 43 different times and tallied 177 yds, earning them an average of 4.1 yds per attempt.

Regarding getting in the endzone, the Stanford Cardinal have an average of 20.0 points per game. Offensively they average 177.0 yards on the ground giving them a rank of 59th in Division 1. The Cardinal have racked up 286 yards in total for the year. In terms of getting in the endzone, Stanford has totaled 1 touchdown on the ground. Stanford has accumulated 21 1st downs offensively, and they have committed 7 penalties for 70 yards. They have surrendered the football 1 time.

Concerning yards through the air, the Cardinal have conceded 210 yds which ranks them 80th in D-1. They have conceded 210.0 yards per outing through the air in addition to allowing a completion percentage of 67.5%. During the season, they are allowing 306.0 yards per contest ranking them 62nd in the country. They have yielded 2 touchdowns through the air. They are allowing 4.0 yards per run and 96.0 yards on the ground per game on the season. During the season, they have given up 96 yards via the ground game in 1 game. The Cardinal sit in 90th in D-1 concerning team defense, conceding 23.0 PPG.

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The Cougars come into this game with a record of 1-0 for this season. When they last stepped on the field, the Cougars took home the win by a final score of 69-0 when they played the Portland State Vikings. BYU ran the ball for 9.8 yards per attempt, totaling 468 yds on 48 attempts. The Cougars finished the game with 606 yards while they ran 66 plays (9.2 yds per play). The Cougars secondary gave up a completion rate of 69.6%, relinquishing 208 yards on 16 out of 23 through the air. BYU conceded 19 attempts on the ground for 2 yds (0.1 yards per rush).

The BYU Cougars are averaging 606.0 yards per outing, ranking them 5th in D-1. The BYU offense has compiled 55 penalty yards on 5 violations, which ranks 78th in D-1 in terms of helping out the opposition. They hold an average of 468.0 run yards per game. They have been able to obtain 28 1st downs. Regarding their scoring prowess, the Cougars are ranking 2nd in the country with an average of 69.0 PPG. During the season thus far, the Cougars have thrown for 138 yards through the air, giving them a rank of 112th in D-1.

The Cougars are giving up 0.0 points per game, which has them sitting 10th in D-1. BYU has allowed the opposition a total of -5 yards via the ground game. They have given up 56.0 passing yards/contest, ranking them 7th in college football. The Cougars defense has taken the field for 44 plays, which ranks 3rd in college football. They have tallied 1 fumble on the season.

Who will win tonight's Cardinal/Cougars college football game against the spread?

Josh's Pick: Take the Cardinal +18.5

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