TCU Horned Frogs vs Houston Cougars Prediction, 11/22/2025 College Football Picks, Best Bets & Odds

Game: TCU Horned Frogs vs Houston Cougars

Date: Saturday, November 22, 2025

Location: TDECU Stadium in Houston, TX

TV: FOX

Odds/Point Spread: Cougars (-1.0)

Total/Over-Under: 55.5

TDECU Stadium is the location where the Houston Cougars (8-2) will go up against the TCU Horned Frogs (6-4) on Saturday, November 22, 2025. TCU opens this game as 1.0-point dogs from Vegas oddsmakers. The total is set at 55.5.

The TCU Horned Frogs head into this matchup 6-4 for this season. The last time they took the field, the Horned Frogs played against the BYU Cougars and walked away from this one with a loss by a score of 44-13. In the game, they had 57 plays which gave them a total of 298 yards. The TCU Horned Frogs ran the football 34 different times and accrued 115 yards, which came out to an average of 3.4 yards per attempt. When it came to the battle of the line of scrimmage, the Horned Frogs gave up 161 yards on 41 attempts, which calculates to 3.9 yds per run allowed. TCU allowed 9 pass completions on 24 tries for a total of 111 yards, and a completion percentage of 37.5%.

When it comes to getting in the endzone, the TCU Horned Frogs are sitting at 30.7 points per game. As a unit they're maintaining an average of 122.0 yards in the run game which ranks them 108th in the country. The Horned Frogs have earned 4,134 total yards for the year. When it comes to scoring, TCU has compiled 23 passing touchdowns and 15 touchdowns via the ground. TCU has accrued 219 1st downs as a team, and they have been flagged for 65 penalties for 610 yds. They have given the ball to the opposition 15 times.

The Horned Frogs rank 83rd in college football in terms of the opposition scoring, allowing 26.5 points per game. They are allowing 3.4 yards per run and 126.7 rushing yards per game for the year. During the season, they have given up 1,267 yards via the ground game in 10 contests. In terms of yards through the air, the Horned Frogs have allowed 2,470 yards which has them ranked 108th in the nation. They have surrendered 247.0 yards per game via the pass in addition to allowing a completion percentage of 61.6%. For the year, they have yielded 373.7 yards per outing which puts them 74th in Division 1. They have surrendered 19 touchdowns through the air as well as 9 touchdowns on the ground.

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The Cougars come into this matchup with a record of 8-2 this season. The last time they took the field, the Cougars walked away with a victory by a final of 30-27 against the UCF Knights. Houston rushed for 4.3 yds per carry, totaling 210 yds on 49 attempts. The Cougars finished the game with a total of 433 yards and they ran 80 plays (5.4 yards per play). The Cougars pass defense gave up a completion rate of 50.0%, surrendering 136 yds on 15 for 30 through the air. Houston gave up 30 rushing attempts for 146 yds (4.9 yds per rush).

The Houston Cougars maintain an average of 388.3 yards/contest, which has them ranked 68th in the country. The Houston offense has 436 yds of penalties on 51 infractions, which has them sitting 108th in Division 1 in terms of hurting your team. They are averaging 166.2 run yards per game and have run for 1,662 yards for this year. They have thrown 8 interceptions while surrendering 4 fumbles and they have been able to tally 209 first downs. Concerning how much they score, the Cougars rank 60th in Division 1 scoring 29.5 PPG. During the season thus far, the Cougars have compiled 2,221 yards through the air as well as an average of 222.1 passing yards per game, ranking them 76th in the country.

The Cougars are surrendering 22.1 PPG, which has them 46th in the country. Houston has given up a total of 1,355 yards on the ground (135.5 yards per contest) and 15 touchdowns via the rush so far this season. They have surrendered 10 touchdowns via the pass in addition to 197.6 yards per outing, which has them sitting 41st in college football. The Cougars defense has been on the field for 664 plays, which has them ranked 62nd in Division 1. Their defense has compiled 3 fumbles recovered and 8 interceptions this season. In total, they have conceded 221 points.

Who will win tonight's Horned Frogs/Cougars college football game against the spread?

Tony's Pick: Take the Cougars -1.0

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