Troy Trojans vs Clemson Tigers Prediction, 9/6/2025 College Football Picks, Best Bets & Odds

Game: Troy Trojans vs Clemson Tigers

Date: Saturday, September 6, 2025

Location: Memorial Stadium in Clemson, SC

TV: ESPN/ESPN+

Odds/Point Spread: Tigers (-33.5)

Total/Over-Under: 52

The Clemson Tigers (0-1) will compete against the Troy Trojans (1-0) at Memorial Stadium on Saturday, September 6, 2025. Clemson opens this contest as 33.5-point favorites. The betting total is set at 52.

The Troy Trojans step onto the field holding a record of 1-0 for this year. The last time they took the field, the Trojans played against the Nicholls State Colonels and notched a win by a score of 38-20. When it came to stopping the run, the Trojans conceded 65 yards on 25 tries, which averages out to 2.6 yards per run allowed. Troy relinquished 21 pass completions on 27 attempts for 184 yards, and a completion rate of 77.8%. Once the final whistle blew, they ran 68 plays which totaled 416 yds. The Troy Trojans rushed the ball a total of 44 different times and recorded 272 yds, which had them averaging 6.2 yards per attempt.

When it comes to scoring points, the Troy Trojans have an average of 38.0 points per contest. As a team they average 272.0 yards on the ground which is 17th in D-1. The Trojans have earned 416 total yards this year. In terms of notching touchdowns, Troy has amassed 3 touchdowns via the pass and 2 touchdowns via the ground. Troy has a total of 23 1st downs, and they have been hurt by 8 infractions for 100 yds. They have yet to turn the ball over.

The Trojans sit in 83rd in college football in terms of the opposition scoring, conceding 20.0 points per contest. Opposing teams are running for an average of 2.6 yards per rush on the ground and 65.0 rushing yards per game on the campaign. For the year, they have conceded 65 rushing yards through 1 game. Regarding yards through the air, the Trojans are giving up 184 yards which puts them in 67th in the nation. They are giving up 184.0 yards per contest via the pass and allowed a completion percentage of 77.8%. For the season, they are giving up 249.0 yards/outing putting them at 41st in the nation. They have given up 1 touchdown by air and 1 touchdown via the ground game.

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The Tigers head into this matchup 0-1 for this season. In their last game, the Tigers took a loss by a score of 17-10 against the LSU Tigers. Clemson conceded 31 running attempts for 108 yards (3.5 yards per rush). The Tigers passing defense conceded a completion percentage of 74.4%, surrendering 248 yds on 29 for 39 passing. The Tigers finished the game with 261 yds and they ran 58 plays (4.5 yds per play). Clemson rushed for 1.6 yards per carry, finishing with a total of 31 yards on 20 carries.

In relation to their scoring prowess, the Tigers are sitting 119th in D-1 averaging 10.0 points per outing. The Clemson Tigers hold an average of 261.0 yards per contest, which has them sitting 116th in D-1. The Clemson offense has 57 penalty yards on 6 violations, which ranks 74th in college football in terms of helping out the opposition. They have been able to earn 13 1st downs. During the season so far, the Tigers have a total of 230 passing yards, ranking them 65th in the nation. They have an average of 31.0 yards per game.

The Tigers are giving up 17.0 points per game, which puts them 81st in college football. Clemson has allowed a total of 108 rushing yards. They have conceded 1 touchdown via the pass and 248.0 yards per game, ranking them 104th in the nation. The Tigers defense has participated in 70 plays, ranking them 92nd in the country. Their defense has 2 fumbles.

Who will win tonight's Trojans/Tigers college football game against the spread?

Guy's Pick: Take the Tigers -33.5

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