Tulane Green Wave vs Ole Miss Rebels Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

Game: Tulane Green Wave vs Ole Miss Rebels

Date: Saturday, September 20, 2025

Location: Vaught-Hemingway Stadium in Oxford, MS

TV: ESPN

Odds/Point Spread: Rebels (-12.0)

Total/Over-Under: 61.5

The Tulane Green Wave (2-0) are hitting the road to Vaught-Hemingway Stadium on Saturday, September 20, 2025 where they will attempt to beat the Ole Miss Rebels (3-0). Ole Miss opens as 12.0-point favorites. The over/under is set at 61.5.

The Tulane Green Wave step onto the field holding a record of 2-0 for this season. The last time they stepped onto the field, the Green Wave went up against the Duke Blue Devils and earned the victory with a final of 34-27. When the final whistle blew, they ran 63 plays which totaled 426 yds. The Tulane Green Wave rushed the ball a total of 38 different times and compiled 156 yds, which had them averaging 4.1 yards per attempt. When it came to the battle of the line of scrimmage, the Green Wave conceded 139 yards on 24 tries, which averages out to 5.8 yds per rush surrendered. Tulane conceded 30 completions on 51 tries for 313 yards, and a completion rate of 58.8%.

When talking about getting in the endzone, the Tulane Green Wave are averaging 30.0 points per contest. As a team they are averaging 222.0 yards in the run game ranking them 24th in D-1. The Green Wave have earned 1,253 total yards for the season. In terms of getting in the endzone, Tulane has compiled 2 passing touchdowns and 8 touchdowns via the ground. Tulane has accumulated 68 1st downs as a unit, and they have been called for 24 infractions for 242 yds. They have surrendered the ball 2 times.

When talking about passing yardage, the Green Wave have conceded 705 yds which ranks them 99th in the country. They have relinquished 235.0 yards per outing via the pass and giving up a completion percentage of 59.5%. During this campaign, they have relinquished 370.0 yards per game putting them 91st in D-1. They have surrendered 5 touchdowns by air and 2 touchdowns running the ball. Opposing teams are running for an average of 4.4 yards per run and 135.0 yards on the ground per game this year. For the year, they have conceded 405 yards via the ground game in 3 games. The Green Wave rank 64th in Division 1 in terms of the opposition scoring, giving up 20.3 points per game.

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The Rebels head into this matchup 3-0 for this year. When they last played, the Rebels took home the win by a final score of 41-35 against the Arkansas Razorbacks. The Rebels finished the contest with a total of 475 yards while running 70 plays (6.8 yards per play). Ole Miss ran for 3.0 yds per carry, finishing the contest with 118 yds on 40 carries. Ole Miss allowed 37 running attempts for 221 yards (6.0 yds per carry). The Rebels secondary gave up a completion rate of 62.9%, surrendering 305 yds on 22 for 35 through the air.

When looking at the points being put on the board, the Rebels are ranking 17th in the nation holding an average of 44.7 points per contest. The Ole Miss Rebels hold an average of 541.7 yards/game, ranking them 11th in college football. The Ole Miss offense has accrued 200 penalty yards on 22 infractions, ranking them 31st in college football in terms of helping out the opposition. They have thrown 4 interceptions and they have been able to tally 79 1st downs. For the year so far, the Rebels have a total of 992 yards through the air in addition to holding an average of 330.7 passing yards per game, which has them sitting 14th in Division 1. They are averaging 211.0 run yards per game and have toted the ball for 633 yards for the season.

Ole Miss has given up a total of 584 yards on the ground (194.7 yards per game) in addition to 6 touchdowns rushing for the year. They have given up 2 touchdowns via the pass as well as 187.0 yards per outing, which has them ranked 47th in college football. Overall, they have conceded 65 points. They have tallied 1 fumble and 1 interception over the course of the season. The Rebels defense has taken the field for 202 plays, which ranks 85th in D-1. The Rebels are relinquishing 21.7 PPG, which has them 70th in the country.

Who will win tonight's Green Wave/Rebels college football game against the spread?

Josh's Pick: Take the Rebels -12.0

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