UCLA Bruins vs Michigan State Spartans Prediction, 10/11/2025 College Football Picks, Best Bets & Odds
Game: UCLA Bruins vs Michigan State Spartans
Date: Saturday, October 11, 2025
Location: Spartan Stadium in East Lansing, MI
TV: BTN
Odds/Point Spread: Spartans (-7.5)
Total/Over-Under: 55.5
Spartan Stadium is the location where the Michigan State Spartans (3-2) will meet the UCLA Bruins (1-4) on Saturday, October 11, 2025. Michigan State opens this matchup as 7.5-point favorites. The over/under is set at 55.5.
The UCLA Bruins head into this matchup 1-4 for this season. The last time they stepped onto the field, the Bruins played the Penn State Nittany Lions and earned the victory with a final of 42-37. The UCLA Bruins ran the football 53 times and totaled 269 yds, earning them an average of 5.1 yards per tote. At the end of the game, they had 77 plays which gave them a total of 435 yards. UCLA gave up 19 pass completions on 26 attempts for a total of 200 yards, and a completion rate of 73.1%. When it came to stopping the run, the Bruins gave up 157 yds on 31 attempts, which is an average of 5.1 yds per run allowed.

When it comes to scoring points, the UCLA Bruins hold an average of 19.8 points per contest. Offensively they hold an average of 153.2 yards on the ground which is 74th in D-1. The Bruins have earned 1,720 yards in total for the season. When it comes to distribution of touchdowns, UCLA has earned 6 passing touchdowns and 4 rushing touchdowns. UCLA has earned 96 1st downs as a unit, and they have been hurt by 41 penalties for 370 yds. They have turned the football over 4 different times.
The Bruins are sitting in 124th in D-1 concerning the opposition scoring, allowing 32.4 points per game. The opposition is running for an average of 5.3 yards per tote and 217.6 yards on the ground per contest so far this season. For the season, they have conceded 1,088 rushing yards through 5 games. When talking about yards through the air, the Bruins have conceded 876 yards which ranks them 24th in college football. They have conceded 175.2 yards per outing via the pass in addition to giving up a completion percentage of 73.1%. In total, they have allowed 392.8 yards per contest putting them at 97th in Division 1. They have surrendered 10 touchdowns through the air as well as 11 touchdowns on the ground.
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The Spartans head into this game 3-2 this season. The last time they took the field, the Spartans walked away with a loss by a score of 38-27 when they faced the Nebraska Cornhuskers. Michigan State rushed for 2.2 yards per tote, finishing the contest with 84 yards on 38 attempts. The Spartans finished the game with a total of 240 yards while they ran 68 plays (3.5 yards per play). The Spartans pass defense conceded a completion percentage of 66.7%, relinquishing 194 yards on 16 for 24 passing. Michigan State gave up 31 rushing attempts for 67 yards (2.2 yds per rush).
When looking at how much they score, the Spartans rank 51st in Division 1 holding an average of 32.8 points per outing. The Michigan State Spartans are averaging 347.4 yards per game, which has them ranked 100th in college football. The Michigan State offense has racked up 203 penalty yards on 24 violations, which has them sitting 113th in college football in terms of giving up free yards. They have thrown 4 interceptions while conceding 3 fumbles and they have recorded 101 first downs. For the year thus far, the Spartans have thrown for a total of 1,037 passing yards as well as holding an average of 207.4 passing yards per game, putting them at 91st in the nation. They have an average of 140.0 yards per game on the ground and have run for 700 yards in total.
The Spartans are allowing 30.6 PPG, ranking them 114th in college football. Michigan State has given up a total of 549 yards rushing (109.8 yards per outing) and 8 touchdowns via the rush so far this year. They have conceded 10 touchdowns via the pass in addition to 249.6 yards per outing, which has them sitting 110th in Division 1. The Spartans defense has been on the field for 309 plays, which has them ranked 28th in the nation. They have compiled 2 fumbles and 3 interceptions this year. Overall, they have relinquished 153 total points.
Who will win tonight's Bruins/Spartans college football game against the spread?
Guy's Pick: Take the Bruins +7.5
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Additional Resources:
Michigan State Spartans - Twitter
UCLA Bruins - Twitter