UCLA Bruins vs Northwestern Wildcats Prediction, 9/27/2025 College Football Picks, Best Bets & Odds

Game: UCLA Bruins vs Northwestern Wildcats

Date: Saturday, September 27, 2025

Location: Martin Stadium in Evanston, IL

TV: BTN

Odds/Point Spread: Wildcats (-6.5)

Total/Over-Under: 45

Martin Stadium is where the Northwestern Wildcats (1-2) will take on the UCLA Bruins (0-3) on Saturday, September 27, 2025. UCLA opens this contest as 6.5-point underdogs. The betting total is set at 45.

The UCLA Bruins head into this matchup 0-3 for this season. In their last matchup, the Bruins took on the New Mexico Lobos and took a loss by a final of 35-10. The UCLA Bruins ran the rock 22 times and had 109 yards, which came out to an average of 5.0 yards per tote. When the final whistle blew, they had 56 plays which gave them 326 yards. UCLA allowed 12 pass completions on 17 tries for 152 yards, and a completion rate of 70.6%. When it came to stopping the run, the Bruins gave up 298 yds on 46 tries, which is an average of 6.5 yards per run allowed.

The Bruins have earned 974 total yards for the year. In terms of getting the ball in the endzone, UCLA has earned 3 touchdowns via the pass and 1 touchdown on the ground. They have surrendered the football 4 times. UCLA has accounted for 56 first downs as a unit, and they have committed 30 infractions for 275 yards. Offensively they're averaging 122.0 yards on the ground ranking this team at 105th in college football. Regarding scoring, the UCLA Bruins hold an average of 14.3 points per game.

When it comes to yards via the pass, the Bruins are allowing 561 yds which has them ranked 25th in the country. They have yielded 187.0 yards per outing through the air as well as allowing a completion percentage of 75.1%. Overall, they are conceding 431.0 yards per contest putting them 123rd in the nation. They have surrendered 7 touchdowns through the air and 8 touchdowns on the ground. Opposing teams are running for an average of 5.5 yards per rush on the ground and 244.0 yards on the ground per contest on the season. For the season, they have given up 732 rushing yards through 3 contests. The Bruins are ranked 127th in the nation in terms of team defense, giving up 36.0 PPG.

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The Wildcats head into this game 1-2 for this year. For their last game, the Wildcats took a defeat with a final score of 34-14 when they played the Oregon Ducks. Northwestern ran the ball for 4.8 yards per carry, finishing with 178 yds on 37 attempts. The Wildcats ended up finishing with 313 yards and they ran 59 plays (5.3 yards per play). The Wildcats secondary gave up a completion rate of 73.1%, relinquishing 197 yds on 19 for 26 passing. Northwestern gave up 30 running attempts for 176 yards (5.9 yards per carry).

When looking at the points being put on the board, the Wildcats currently rank 115th in Division 1 holding an average of 19.7 points per game. The Northwestern Wildcats are averaging 358.7 yards per game, ranking them 96th in Division 1. The Northwestern offense has 100 yds of penalties on 14 violations, which is good for 122nd in D-1 in terms of hurting your team. They have tossed 6 interceptions while allowing opponents to recover 2 fumbles and they have tallied 58 1st downs. For the year thus far, the Wildcats currently have a total of 541 passing yards as well as holding an average of 180.3 passing yards per outing, which has them sitting 111th in Division 1. They maintain an average of 178.3 yards via the ground game and have run for 535 yards in total.

Northwestern has allowed a total of 515 rushing yards (171.7 yards/game) and 4 touchdowns on the ground for the campaign. They have surrendered 3 touchdowns through the air as well as 153.0 yards per contest, which has them in 21st in the country. In total, they have given up 64 points in total. Their defense has earned 0 fumbles and 2 picks on the season. The Wildcats defense has been on the field for 180 plays, which ranks 11th in the nation. The Wildcats are conceding 21.3 points per contest, which has them 61st in the nation.

Who will win tonight's Bruins/Wildcats college football game against the spread?

Guy's Pick: Take the Bruins +6.5

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