USF Bulls vs Florida Gators Prediction, 9/6/2025 College Football Picks, Best Bets & Odds

Game: USF Bulls vs Florida Gators

Date: Saturday, September 6, 2025

Location: Ben Hill Griffin Stadium in Gainesville, FL

TV: ESPN/ESPN+

Odds/Point Spread: Gators (-17.5)

Total/Over-Under: 56.5

The Florida Gators (1-0) welcome the USF Bulls (1-0) at Ben Hill Griffin Stadium on Saturday, September 6, 2025. USF opens this contest as 17.5-point dogs. The over/under is set at 56.5.

The USF Bulls come into this game with a record of 1-0 this year. The last time they took the field, the Bulls faced the Boise State Broncos and walked away with a win by a score of 34-7. The USF Bulls ended up rushing 28 times and had 117 yards, which had them averaging 4.2 yards per carry. Overall, they tallied 53 plays which gave them 372 yds. USF surrendered 27 completions on 48 attempts for 256 yds, and a completion percentage of 56.3%. On the ground, the Bulls gave up 122 yds on 38 attempts, which is an average of 3.2 yards per run allowed.

When talking about scoring points, the USF Bulls have an average of 34.0 points per game. Offensively they hold an average of 117.0 yards rushing which is 91st in the nation. The Bulls have racked up 372 total yards for the year. When it comes to notching touchdowns, USF has compiled 1 touchdown through the air and 3 touchdowns via the ground. USF has accounted for 15 first downs as a unit, and they have committed 7 infractions for 56 yards. They haven't turned the ball over yet.

In terms of passing yards, the Bulls have given up 256 yards which ranks them 105th in college football. They are giving up 256.0 yards per game via the pass as well as giving up a completion percentage of 56.3%. For the year, they have yielded 378.0 yards per outing putting them at 100th in Division 1. They have granted 1 touchdown via the pass. They are allowing teams to run for an average of 3.2 yards per rushing attempt and 122.0 rushing yards per game so far this year. Overall, they have allowed 122 rushing yards through 1 outing. The Bulls are sitting in 23rd in Division 1 in terms of their opponents scoring, conceding 7.0 PPG.

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The Gators head into this game 1-0 for this season. In their last game, the Gators walked away with a victory by a final of 55-0 against the LIU Sharks. Florida allowed 32 running attempts for 37 yards (1.2 yards per carry). The Gators passing defense conceded a completion percentage of 36.4%, surrendering 49 yds on 4 out of 11 passing. The Gators finished the contest with a total of 451 yds and they ran 74 plays (6.1 yds per play). Florida ended up running for 5.3 yds per carry, finishing the game with 200 yds on 38 carries.

Regarding their scoring prowess, the Gators are 10th in D-1 with 55.0 points per contest. The Florida Gators hold an average of 451.0 yards/game, which has them ranked 42nd in Division 1. The Florida offense has yet to commit a penalty this year. They have been able to obtain 28 1st downs. For the season thus far, the Gators have compiled 251 passing yards, which has them ranked 45th in Division 1. They hold an average of 200.0 yards per game.

The Gators are relinquishing 0.0 PPG, which puts them 9th in the nation. Florida has given up a total of 37 yards rushing. They have given up 49.0 passing yards per contest, ranking them 5th in the country. The Gators defense has taken the field for 43 plays, which has them sitting 2nd in the nation. They have earned 2 fumbles so far this year.

Who will win tonight's Bulls/Gators college football game against the spread?

Guy's Pick: Take the Gators -17.5

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