USF Bulls vs Memphis Tigers Prediction, 10/25/2025 College Football Picks, Best Bets & Odds

Game: USF Bulls vs Memphis Tigers

Date: Saturday, October 25, 2025

Location: Simmons Bank Liberty Stadium in Memphis, TN

TV: ESPN2

Odds/Point Spread: Tigers (+5.0)

Total/Over-Under: 63.5

The Memphis Tigers (6-1) will take on the USF Bulls (6-1) at Simmons Bank Liberty Stadium on Saturday, October 25, 2025. USF is 5.0-point favorites. The betting total comes in at 63.5.

The USF Bulls come into this game with a record of 6-1 this season. The last time they took the field, the Bulls played against the Florida Atlantic Owls and earned the victory with a final of 48-13. When it came to stopping the run, the Bulls gave up 23 yards on 30 tries, which calculates to 0.8 yards per run allowed. USF relinquished 41 pass completions on 58 tries for a total of 289 yds, and a completion rate of 70.7%. When all was said and done, they had 76 plays which totaled 522 yds. The USF Bulls ran the rock 51 times and accounted for 259 yards, earning them an average of 5.1 yds per carry.

When it comes to putting the ball in the endzone, the USF Bulls hold an average of 41.7 PPG. As a team they average 215.6 yards rushing ranking this team at 16th in college football. The Bulls have tallied 3,332 yards in total for the year. When it comes to getting the ball in the endzone, USF has earned 18 touchdowns through the air and 16 rushing touchdowns. USF has a total of 164 1st downs as a unit, and they have been called for 46 infractions for 436 yds. They have surrendered the football 10 different times.

When it comes to passing yards, the Bulls have allowed 1,858 yds which puts them in 124th in Division 1. They have yielded 265.4 yards per outing via the pass and allowed a completion percentage of 65.1%. During the season, they have relinquished 378.3 yards per game which has them sitting 82nd in college football. They have relinquished 10 touchdowns via the pass as well as 10 touchdowns via the ground game. The opposition is running for an average of 3.3 yards per rushing attempt and 112.9 rushing yards per contest on the season. In total, they have conceded 790 yards via the running game in 7 games. The Bulls are ranked 57th in the nation concerning the opposition scoring, giving up 23.0 points per contest.

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The Tigers head into this matchup 6-1 this year. When they last stepped on the gridiron, the Tigers took a defeat with a final score of 31-24 when they faced the UAB Blazers. Memphis rushed the ball for 4.8 yds per carry, finishing the contest with 119 yds on 25 carries. The Tigers finished the contest with a total of 362 yds while they ran 60 plays (6.0 yds per play). The Tigers secondary gave up a completion rate of 74.1%, relinquishing 251 yds on 20 out of 27 passing. Memphis surrendered 41 attempts on the ground for 219 yds (5.3 yards per rush).

When it comes to their scoring prowess, the Tigers currently sit 14th in D-1 averaging 38.1 points per game. The Memphis Tigers maintain an average of 437.6 yards/outing, ranking them 31st in college football. The Memphis offense has racked up 309 penalty yds on 36 infractions, which is 106th in college football in terms of giving up free yards. They have thrown 6 interceptions while letting opponents recover 2 fumbles and they have tallied 165 1st downs. During the season to this point, the Tigers currently have a total of 1,512 passing yards along with an average of 216.0 passing yards per contest, which has them sitting 85th in the country. They are averaging 221.6 yards via the ground game and have rushed for 1,551 yards for the season.

The Tigers are surrendering 18.3 PPG, which has them 25th in Division 1. Memphis has surrendered a total of 747 yards on the ground (106.7 yards per game) in addition to 8 touchdowns rushing this year. They have conceded 7 touchdowns through the air in addition to 228.4 yards/game, which has them ranked 82nd in Division 1. The Tigers defense has been on the field for 451 plays, ranking them 53rd in the country. They have totaled 4 fumbles and 10 interceptions on the year. Overall, they have conceded 128 points in total.

Who will win tonight's Bulls/Tigers college football game against the spread?

Tony's Pick: Take the Tigers +5.0

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