Vanderbilt Commodores vs Virginia Tech Hokies Prediction, 9/6/2025 College Football Picks, Best Bets & Odds

Game: Vanderbilt Commodores vs Virginia Tech Hokies

Date: Saturday, September 6, 2025

Location: Lane Stadium in Blacksburg, VA

TV: ESPN/ESPN+

Odds/Point Spread: Hokies (-1.0)

Total/Over-Under: 47.5

The Vanderbilt Commodores (1-0) are traveling to Lane Stadium on Saturday, September 6, 2025 where they will compete against the Virginia Tech Hokies (0-1). Virginia Tech opens as 1.0-point favorites. The betting total comes in at 47.5.

The Vanderbilt Commodores come into this game with a record of 1-0 for this season. In their last matchup, the Commodores went up against the Charleston Southern Buccaneers and earned the victory with a final of 45-3. The Vanderbilt Commodores ran the ball 31 times and amassed 201 yards, which earned them an average of 6.5 yards per carry. In the game, they had 59 plays which converted into 481 yds. Vanderbilt conceded 10 pass completions on 19 attempts for a total of 88 yds, and a completion rate of 52.6%. In the running game, the Commodores conceded 47 yards on 27 attempts, which averages out to 1.7 yds per run surrendered.

The Commodores have earned 481 total yards over the course of this year. When it comes to scoring, Vanderbilt has amassed 3 touchdowns via the pass and 3 touchdowns via the ground. They haven't turned the ball over yet. Vanderbilt has a total of 25 first downs as an offense, and they have been called for 7 infractions for 60 yds. As a unit they're holding an average of 201.0 yards on the ground which is 42nd in the country. Concerning getting in the endzone, the Vanderbilt Commodores are averaging 45.0 points per game.

In terms of passing yards, the Commodores have given up 88 yds which has them ranked 18th in the country. They have conceded 88.0 yards per game via the pass and conceding a completion percentage of 52.6%. Overall, they have surrendered 135.0 yards per outing putting them 8th in D-1. They have yet to surrender a touchdown on defense. They are allowing teams to run for an average of 1.7 yards per running attempt and 47.0 rushing yards per contest so far this season. Over the course of this season, they have given up 47 rushing yards through 1 outing. The Commodores rank 12th in the country when it comes to team defense, conceding 3.0 PPG.

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The Hokies come into this game with a record of 0-1 for this season. The last time they took the field, the Hokies walked away with a loss by a score of 24-11 when they faced the South Carolina Gamecocks. Virginia Tech allowed 37 rush attempts for 119 yards (3.2 yds per carry). The Hokies pass defense gave up a completion rate of 63.2%, surrendering 209 yds on 12 for 19 through the air. The Hokies ended up finishing with 336 yards while they ran 72 plays (4.7 yards per play). Virginia Tech ran the ball for 3.1 yds per carry, finishing the contest with 115 yards on 37 carries.

The Virginia Tech Hokies are averaging 336.0 yards per outing, which is good for 91st in the country. The Virginia Tech offense has 40 yds of penalties on 4 infractions, which ranks 111th in Division 1 in terms of helping out the other team. They have an average of 115.0 yards per game. They have been able to obtain 19 1st downs. When it comes to their ability to score points, the Hokies are ranked 117th in the nation holding an average of 11.0 points per contest. During the season so far, the Hokies have thrown for 221 yards via the pass, which has them ranked 69th in Division 1.

Virginia Tech has given up a total of 119 yards via the ground game. They have given up 1 touchdown through the air and 209.0 yards/outing, which has them ranked 84th in Division 1. They haven't forced a turnover. The Hokies defense has been on the field for 56 plays, which has them sitting 29th in D-1. The Hokies are giving up 24.0 points per game, which puts them 93rd in the nation.

Who will win tonight's Commodores/Hokies college football game against the spread?

Tony's Pick: Take the Commodores +1.0

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