Virginia Tech Hokies vs Florida State Seminoles Prediction, 11/15/2025 College Football Picks, Best Bets & Odds
Game: Virginia Tech Hokies vs Florida State Seminoles
Date: Saturday, November 15, 2025
Location: Doak Campbell Stadium in Tallahassee, FL
TV: ACC Network
Odds/Point Spread: Seminoles (-13.5)
Total/Over-Under: 55.5
The Florida State Seminoles (4-4) will go up against the Virginia Tech Hokies (3-6) at Doak Campbell Stadium on Saturday, November 15, 2025. Florida State opens this contest as 13.5-point favorites from Vegas oddsmakers. The total is set at 55.5.
The Virginia Tech Hokies step onto the field holding a record of 3-6 for this season. In their last game, the Hokies played against the Louisville Cardinals and went home with a loss by a final score of 28-16. The Virginia Tech Hokies ran the ball 40 times and compiled 164 yds, which had them averaging 4.1 yards per tote. On the day, they tallied 64 plays for 240 yards. Virginia Tech surrendered 19 completions on 28 attempts for 136 yds, and a completion percentage of 67.9%. In the running game, the Hokies gave up 235 yds on 34 attempts, which is an average of 6.9 yds per run allowed.

The Hokies have racked up 3,230 total yards over the course of this year. When it comes to getting the ball in the endzone, Virginia Tech has amassed 15 touchdowns via the pass and 10 rushing touchdowns. They have surrendered the ball 9 different times. Virginia Tech has tallied 181 first downs offensively, and they have committed 65 penalties for 593 yards. As a unit they average 182.0 yards in the run game giving them a rank of 43rd in the nation. Regarding putting the ball in the endzone, the Virginia Tech Hokies have an average of 24.3 points per outing.
In terms of passing yardage, the Hokies are giving up 1,986 yds which has them sitting in 86th in D-1. They have allowed 220.7 yards per game through the air in addition to allowing a completion percentage of 67.4%. In total, they are surrendering 367.6 yards per outing which ranks them 68th in D-1. They have yielded 12 touchdowns through the air in addition to 20 touchdowns on the ground. The opposition is running for 4.3 yards per rush and 146.9 yards on the ground per contest for the year. During the season, they have conceded 1,322 yards via the running game in 9 games. The Hokies rank 104th in college football concerning the opposition scoring, giving up 29.7 PPG.
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The Seminoles head into this matchup 4-4 for this season. For their last game, the Seminoles took a defeat with a final score of 24-10 against the Clemson Tigers. Florida State allowed 36 run attempts for 98 yards (2.7 yds per carry). The Seminoles passing defense gave up a completion percentage of 74.1%, surrendering 221 yards on 20 for 27 passing. The Seminoles ended up finishing with 360 yds while running 69 plays (5.2 yds per play). Florida State rushed the ball for 4.2 yds per attempt, finishing with a total of 110 yards on 26 carries.
When discussing how much they score, the Seminoles rank 7th in the country with an average of 40.0 PPG. The Florida State Seminoles maintain an average of 510.5 yards/contest, which has them ranked 1st in the country. The Florida State offense has totaled 424 penalty yds on 47 infractions, which is 96th in D-1 in terms of giving up free yards. They have tossed 5 picks while conceding 6 fumbles and they have been able to record 200 first downs. For the year so far, the Seminoles have thrown for a total of 2,154 passing yards as well as holding an average of 269.3 passing yards per game, which has them sitting 28th in college football. They average 241.3 yards per game via the ground game and have toted the ball for 1,930 yards for the season.
Florida State has allowed a total of 915 yards rushing (114.4 yards per contest) and 7 touchdowns on the ground so far this year. They have given up 13 touchdowns via the pass and 202.9 yards/outing, which puts them in 44th in the country. Over the course of the season, they have surrendered 165 total points. Their defense has tallied 1 fumbles and 10 interceptions this year. The Seminoles defense has participated in 528 plays, which is good for 28th in D-1. The Seminoles are allowing 20.6 points per game, which has them sitting 32nd in the country.
Who will win tonight's Hokies/Seminoles college football game against the spread?
Guy's Pick: Take the Hokies +13.5
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Additional Resources:
Florida State Seminoles - Twitter
Virginia Tech Hokies - Twitter

