Wyoming Cowboys vs San Diego State Aztecs Prediction, 11/1/2025 College Football Picks, Best Bets & Odds

Game: Wyoming Cowboys vs San Diego State Aztecs

Date: Saturday, November 1, 2025

Location: Snapdragon Stadium in San Diego, CA

TV: CBSSN

Odds/Point Spread: Aztecs (-11.0)

Total/Over-Under: 41.5

Snapdragon Stadium is the location where the San Diego State Aztecs (6-1) will take on the Wyoming Cowboys (3-4) on Saturday, November 1, 2025. San Diego State opens as 11.0-point favorites from oddsmakers. The total is 41.5.

The Wyoming Cowboys come into this matchup with a record of 3-4 this year. In their last contest, the Cowboys took the field against the Colorado State Rams and took home the win by a score of 28-0. On the day, they ran 59 plays which converted into 372 yds. The Wyoming Cowboys ran the rock 34 different times and compiled 212 yds, which had them averaging 6.2 yds per carry. In the running game, the Cowboys gave up 94 yds on 27 attempts, which calculates to 3.5 yards per rush allowed. Wyoming surrendered 19 completions on 34 tries for 211 yds, and a completion percentage of 55.9%.

The Cowboys have tallied 2,927 total yards for the season. In terms of scoring, Wyoming has earned 11 touchdowns via the pass and 9 rushing touchdowns. They have turned the ball over 12 times. Wyoming has tallied 163 1st downs as an offense, and they have been flagged for 53 infractions for 451 yds. As a team they're maintaining an average of 157.3 yards on the ground which ranks them 65th in D-1. Concerning scoring points, the Wyoming Cowboys hold an average of 21.0 PPG.

In terms of passing yards, the Cowboys have allowed 1,470 yds which ranks them 30th in college football. They are giving up 183.8 yards per game through the air and allowed a completion percentage of 55.3%. For the season, they have given up 342.8 yards per game putting them at 47th in D-1. They have allowed 10 touchdowns via the pass in addition to 8 touchdowns on the ground. They are allowing 4.5 yards per rush on the ground and 159.0 rushing yards per game so far this season. Over the course of this season, they have allowed 1,272 rushing yards through 8 games. The Cowboys sit in 32nd in college football regarding their opponents scoring, conceding 19.8 points per game.

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The Aztecs head into this game 6-1 for this year. For their last game, the Aztecs took home the win by a final score of 23-0 against the Fresno State Bulldogs. San Diego State allowed 23 attempts on the ground for 45 yards (2.0 yds per rush). The Aztecs pass defense gave up a completion percentage of 47.6%, surrendering 182 yards on 20 for 42 through the air. The Aztecs ended up finishing with 332 yds on 65 plays (5.1 yards per play). San Diego State ran the football for 4.5 yards per tote, finishing the contest with 208 yds on 46 attempts.

The San Diego State Aztecs average 363.9 yards/game, which is good for 90th in D-1. The San Diego State offense has 409 penalty yds on 45 violations, which ranks 88th in D-1 in terms of helping out the other team. They average 184.1 run yards per game and have run for 1,289 yards for the season. They have thrown 3 interceptions while conceding 1 fumbles and they have been able to earn 133 first downs. In terms of this team's ability to score points, the Aztecs are sitting 61st in D-1 averaging 29.6 points per outing. During this campaign so far, the Aztecs have earned 1,258 passing yards as well as an average of 179.7 passing yards per game, which has them sitting 115th in the nation.

The Aztecs are giving up 10.4 points per contest, which puts them 2nd in D-1. San Diego State has conceded a total of 619 rushing yards (88.4 yards per contest) and 2 touchdowns on the ground for the season. They have surrendered 6 touchdowns through the air as well as 166.6 yards per game, which has them ranked 16th in D-1. The Aztecs defense has taken part in 453 plays, which is good for 15th in the country. Their defense has compiled 1 fumble and 7 picks this year. Over the course of the season, they have surrendered 73 pts.

Who will win tonight's Cowboys/Aztecs college football game against the spread?

Josh's Pick: Take the Aztecs -11.0

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