Clemson Tigers vs Florida State Seminoles Prediction, 10/31/2026 College Football Picks, Best Bets & Odds
Game: Clemson Tigers vs Florida State Seminoles
Date: Saturday, October 31, 2026
Location: Doak Campbell Stadium in Tallahassee, FL
TV: ACC Network
Odds/Point Spread: Seminoles (-6.5)
Total/Over-Under: 49.5
Doak Campbell Stadium is the location where the Florida State Seminoles (3-4) will take on the Clemson Tigers (4-3) on Saturday, October 31, 2026. Florida State opens this game as 6.5-point favorites from oddsmakers. The betting total comes in at 49.5.
The Clemson Tigers step onto the field holding a record of 4-3 this season. In their last game, the Tigers played against the Virginia Tech Hokies and walked away from this one with a loss by a score of 20-16. In all, they ran 62 plays which converted into 288 yards. The Clemson Tigers ran the football 36 different times and accumulated 135 yds, which earned them an average of 3.8 yards per attempt. In the running game, the Tigers conceded 70 yards on 37 attempts, which averages out to 1.9 yards per run surrendered. Clemson allowed 21 completions on 33 tries for a total of 164 yards, and a completion percentage of 63.6%.

Concerning getting in the endzone, the Clemson Tigers are averaging 21.4 points per game. As a unit they're averaging 150.6 yards rushing giving them a rank of 79th in the country. The Tigers have tallied 2,332 total yards this season. When it comes to distribution of touchdowns, Clemson has compiled 2 passing touchdowns and 10 rushing touchdowns. Clemson has 138 first downs offensively, and they have committed 50 infractions for 455 yds. They have given the ball to the opposition 11 different times.
The Tigers are ranked 50th in the country regarding team defense, conceding 21.3 points per game. The opposition is running for an average of 3.7 yards per attempt on the ground and 131.3 yards on the ground per game for the campaign. Overall, they have given up 919 yards via the ground game in 7 outings. When talking about passing yards, the Tigers have allowed 1,300 yds which has them sitting in 27th in the country. They have conceded 185.7 yards per outing via the pass and giving up a completion percentage of 57.7%. Over the course of this season, they have relinquished 317.0 yards/outing which ranks them 32nd in Division 1. They have given up 7 touchdowns through the air as well as 8 touchdowns running the ball.
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The Seminoles come into this matchup with a record of 3-4 for this season. In their last game, the Seminoles took a defeat with a final score of 43-35 when they faced the Miami Hurricanes. Florida State ran the ball for 4.1 yards per carry, finishing the contest with 138 yds on 34 attempts. The Seminoles finished the contest with a total of 443 yards while running 64 plays (6.9 yards per play). The Seminoles pass defense allowed a completion rate of 67.6%, surrendering 326 yds on 23 out of 34 passing. Florida State relinquished 44 rushing attempts for 257 yards (5.8 yards per rush).
In relation to this team's ability to score points, the Seminoles currently sit 50th in D-1 averaging 31.6 PPG. The Florida State Seminoles maintain an average of 414.3 yards/contest, which has them sitting 50th in D-1. The Florida State offense has accrued 391 penalty yards on 42 violations, which ranks them 103rd in college football in terms of making mistakes. They have thrown 8 interceptions while allowing opponents to recover 2 fumbles and they have earned 140 1st downs. For the year so far, the Seminoles have a total of 1,639 yards through the air as well as holding an average of 234.1 throwing yards per game, ranking them 64th in the nation. They have an average of 180.1 rushing yards per game and have rushed for 1,261 yards for the year.
The Seminoles are giving up 27.9 points per game, which has them ranked 103rd in the country. Florida State has allowed the opposition a total of 1,250 yards rushing (178.6 yards per outing) and 13 touchdowns rushing so far this year. They have allowed the opposition 12 touchdowns via the pass in addition to 256.3 yards/game, ranking them 124th in the nation. The Seminoles defense has taken the field for 480 plays, which is good for 77th in D-1. Their defense has totaled 2 fumbles and 4 interceptions this season. Overall, they have relinquished 195 points in total.
Who will win tonight's Tigers/Seminoles college football game against the spread?
Guy's Pick: Take the Tigers +6.5
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Additional Resources:
Florida State Seminoles - Twitter
Clemson Tigers - Twitter

