Florida State Seminoles vs Alabama Crimson Tide Prediction, 9/19/2026 College Football Picks, Best Bets & Odds

Game: Florida State Seminoles vs Alabama Crimson Tide

Date: Saturday, September 19, 2026

Location: Bryant-Denny Stadium in Tuscaloosa, AL

TV: ESPN+

Odds/Point Spread: Crimson Tide (-20.5)

Total/Over-Under: 49

The Florida State Seminoles (1-1) are hitting the road to Bryant-Denny Stadium on Saturday, September 19, 2026 where they will compete against the Alabama Crimson Tide (2-0). Alabama opens this matchup as 20.5-point favorites. The total has been set at 49.

The Florida State Seminoles come into this matchup with a record of 1-1 for this year. In their last matchup, the Seminoles faced the SMU Mustangs and walked away from this one with a loss by a score of 27-24. In the running game, the Seminoles gave up 155 yds on 31 attempts, which is 5.0 yds per run allowed. Florida State gave up 26 pass completions on 36 tries for 430 yards, and a completion rate of 72.2%. At the end of the game, they ran 68 plays which converted into 324 yards. The Florida State Seminoles ran the rock 45 different times and compiled 199 yards, which is an average of 4.4 yards per tote.

Regarding scoring, the Florida State Seminoles are averaging 29.0 PPG. As a unit they're averaging 208.0 yards rushing ranking them 39th in the country. The Seminoles have earned 743 total yards for the year. When it comes to getting the ball in the endzone, Florida State has earned 2 touchdowns through the air and 5 touchdowns via the ground. Florida State has earned 36 1st downs as a team, and they have been flagged for 10 infractions for 92 yards. They have given the ball to the opposition 2 different times.

Regarding yards through the air, the Seminoles have allowed 702 yards which puts them in 132nd in D-1. They have surrendered 351.0 yards per game via the pass in addition to giving up a completion percentage of 65.8%. During the season, they are conceding 452.0 yards per outing which ranks them 128th in Division 1. They have relinquished 5 touchdowns through the air in addition to no TD's on the ground. The opposition is running for an average of 3.7 yards per rush and 101.0 yards on the ground per game for the campaign. Over the course of this season, they have conceded 202 rushing yards through 2 games. The Seminoles are ranked 76th in D-1 in terms of team defense, allowing 22.0 points per contest.

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The Crimson Tide come into this matchup with a record of 2-0 for this season. In their last game, the Crimson Tide went home victorious with a score of 45-17 when they faced the Kentucky Wildcats. The Crimson Tide finished the game with a total of 343 yards while they ran 63 plays (5.4 yds per play). Alabama ran for 3.9 yards per tote, finishing with a total of 155 yds on 40 carries. Alabama conceded 32 attempts on the ground for 63 yards (2.0 yds per rush). The Crimson Tide pass defense allowed a completion percentage of 56.3%, relinquishing 146 yards on 18 out of 32 through the air.

The Alabama Crimson Tide have an average of 415.0 yards/game, which has them sitting 65th in the nation. The Alabama offense has 74 penalty yards on 14 infractions, which is good for 60th in the country in terms of helping out the other team. They have an average of 191.0 yards per game on the ground and have run for 382 yards for this season. They have given away 2 picks while surrendering 2 fumbles and they have been able to earn 49 first downs. When looking at their scoring prowess, the Crimson Tide are ranking 21st in the country with an average of 46.5 points per contest. Over the course of the season thus far, the Crimson Tide have thrown for a total of 448 yards via the pass as well as an average of 224.0 throwing yards per contest, which has them ranked 72nd in Division 1.

The Crimson Tide are allowing 13.5 PPG, which has them 35th in the nation. Alabama has yielded a total of 65 rushing yards (32.5 yards per game) as well as 0 touchdown rushing on the campaign. They have allowed the opposition 2 touchdowns from the passing game in addition to 153.0 yards per outing, which has them ranked 36th in the nation. The Crimson Tide defense has been on the field for 105 plays, which is good for 9th in the nation. They have earned 2 fumbles and 2 interceptions for the season.

Who will win tonight's Seminoles/Crimson Tide college football game against the spread?

Tony's Pick: Take the Seminoles +20.5

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