Georgia Southern Eagles vs Clemson Tigers Prediction, 9/12/2026 College Football Picks, Best Bets & Odds

Game: Georgia Southern Eagles vs Clemson Tigers

Date: Saturday, September 12, 2026

Location: Memorial Stadium in Clemson, SC

TV: ESPN+

Odds/Point Spread: Tigers (-21.0)

Total/Over-Under: 55

Memorial Stadium is the site where the Clemson Tigers (0-1) will attempt to beat the Georgia Southern Eagles (1-0) on Saturday, September 12, 2026. Clemson opens this game as 21-point favorites. The over/under has been set at 55.

The Georgia Southern Eagles come into this game with a record of 1-0 this season. In their last contest, the Eagles faced off with the Charleston Southern Buccaneers and walked away with a win by a score of 31-0. In all, they tallied 77 plays for 513 yds. The Georgia Southern Eagles ended up running the ball 30 times and tallied 162 yards, earning them an average of 5.4 yds per carry. When it came to stopping the run, the Eagles gave up 8 yards on 31 tries, which averages out to 0.3 yards per rush surrendered. Georgia Southern gave up 9 pass completions on 29 tries for 109 yards, and a completion rate of 31.0%.

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The Eagles have attained 513 total yards this year. When it comes to notching touchdowns, Georgia Southern has earned 1 touchdown through the air and 3 touchdowns via the ground. They have given the ball to the opposition 1 time. Georgia Southern has a total of 26 1st downs as a team, and they have been called for 6 infractions for 65 yds. As a unit they're averaging 162.0 yards on the ground which has them sitting 70th in Division 1. When it comes to getting in the endzone, the Georgia Southern Eagles are averaging 31.0 points per outing.

The Eagles are ranked 8th in Division 1 when it comes to team defense, giving up 0.0 PPG. They are allowing teams to run for an average of 0.3 yards per rush on the ground and 8.0 rushing yards per game on the year. During the season, they have given up 8 yards via the running game in 1 contest. When talking about passing yards, the Eagles have allowed 109 yds which has them ranked 25th in Division 1. They are giving up 109.0 yards per outing through the air and conceding a completion percentage of 31.0%. Over the course of this year, they are conceding 117.0 yards per contest putting them at 7th in the country. They have yielded no touchdowns through the air as well as no touchdowns running the ball.

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The Tigers head into this game 0-1 this season. In their last game, the Tigers took a defeat with a final score of 51-10 when they played the LSU Tigers. The Tigers finished the game with 145 yds and they ran 48 plays (3.0 yds per play). Clemson rushed the football for 1.5 yards per tote, finishing with 40 yards on 26 attempts. Clemson surrendered 58 attempts on the ground for 309 yards (5.3 yds per rush). The Tigers secondary gave up a completion rate of 61.1%, relinquishing 335 yds on 22 for 36 passing.

In terms of their scoring prowess, the Tigers rank 121st in college football scoring 10.0 points per contest. The Clemson Tigers maintain an average of 145.0 yards/contest, ranking them 134th in college football. The Clemson offense has compiled 41 yds of penalties on 5 infraction, which has them sitting 102nd in college football in terms of giving up free yards. They have thrown 1 pick while losing no fumbles and they have recorded 8 first downs. During this campaign to this point, the Tigers currently sit at 105 passing yards. They maintain an average of 40.0 yards per game via the rush.

The Tigers are relinquishing 51.0 points per game, which puts them 130th in Division 1. Clemson has given up a total of 309 rushing yards and 4 touchdowns by way of the ground game so far this year. They have given up 2 touchdowns via the pass in addition to 335.0 yards per game, which has them ranked 124th in college football. The Tigers defense has taken the field for 94 plays, ranking them 125th in the country. Their defense has tallied no fumbles and 1 interception so far this season.

Who will win tonight's Eagles/Tigers college football game against the spread?

Guy's Pick: Take the Eagles +21.0

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