Louisiana Ragin' Cajuns vs Charlotte 49ers Prediction, 9/26/2026 College Football Picks, Best Bets & Odds

Game: Louisiana Ragin' Cajuns vs Charlotte 49ers

Date: Saturday, September 26, 2026

Location: Jerry Richardson Stadium in Charlotte, NC

TV: ESPN+

Odds/Point Spread: 49ers (+10.0)

Total/Over-Under: 49.5

The Charlotte 49ers (0-3) will take on the Louisiana Ragin' Cajuns (2-1) at Jerry Richardson Stadium on Saturday, September 26, 2026. Louisiana opens this contest as 10-point favorites. The betting total is set at 49.5.

The Louisiana Ragin' Cajuns head into this game 2-1 for this season. In their last game, the Ragin' Cajuns faced the UAB Blazers and earned the victory with a final of 21-14. In the running game, the Ragin' Cajuns conceded 74 yards on 31 attempts, which is an average of 2.4 yards per run allowed. Louisiana surrendered 15 pass completions on 27 attempts for 144 yds, and a completion percentage of 55.6%. When the final whistle blew, they tallied 72 plays for 335 yds. The Louisiana Ragin' Cajuns ended up running the ball 53 different times and had 225 yds, which came out to an average of 4.2 yards per carry.

When it comes to scoring points, the Louisiana Ragin' Cajuns are sitting at 29.7 points per game. As a unit they're averaging 204.7 yards on the ground which has them sitting 39th in Division 1. The Ragin' Cajuns have earned 1,167 total yards for the season. When it comes to getting the ball in the endzone, Louisiana has compiled 1 touchdown through the air and 11 rushing touchdowns. Louisiana has amassed 64 first downs offensively, and they have been called for 19 penalties for 158 yds. They have surrendered the ball 5 times.

When talking about passing yards, the Ragin' Cajuns have allowed 562 yards which has them sitting in 56th in Division 1. They have relinquished 187.3 yards per game via the pass as well as giving up a completion percentage of 59.6%. During this campaign, they have relinquished 302.0 yards/outing which puts them 49th in college football. They have granted 5 touchdowns through the air as well as 2 touchdowns running the ball. They are allowing an average of 3.4 yards per running attempt and 114.7 rushing yards per contest on the season. Overall, they have conceded 344 rushing yards through 3 outings. The Ragin' Cajuns rank 75th in college football concerning team defense, giving up 23.3 PPG.

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The 49ers come into this matchup with a record of 0-3 for this season. In their last game, the 49ers took a defeat with a final score of 26-21 when they faced the Appalachian State Mountaineers. The 49ers finished the contest with 247 yds and they ran 60 plays (4.1 yards per play). Charlotte ran the ball for 1.4 yards per attempt, finishing with 36 yds on 25 attempts. Charlotte gave up 33 run attempts for 90 yards (2.7 yds per rush). The 49ers pass defense allowed a completion rate of 67.4%, relinquishing 345 yds on 29 for 43 through the air.

The Charlotte 49ers maintain an average of 369.0 yards per outing, ranking them 93rd in the nation. The Charlotte offense has totaled 128 yards of penalties on 22 infractions, which is 47th in the country in terms of hurting your team. They maintain an average of 131.7 rushing yards per game and have rushed for 395 yards for the season. They have given away 5 picks while letting opponents recover no fumbles and they have been able to record 53 1st downs. When it comes to their scoring prowess, the 49ers are sitting 107th in D-1 with 23.7 PPG. During this campaign to this point, the 49ers currently have a total of 712 passing yards not to mention holding an average of 237.3 passing yards per contest, putting them at 63rd in Division 1.

The 49ers are surrendering 36.7 PPG, which puts them 130th in the nation. Charlotte has allowed a total of 485 yards rushing (161.7 yards per outing) as well as 10 touchdowns on the ground for the season. They have surrendered 4 touchdowns through the air in addition to 256.7 yards/contest, which has them in 123rd in the nation. The 49ers defense has been on the field for 197 plays, which has them ranked 81st in D-1. They have tallied 1 fumble and 2 interceptions so far this year. This season, they have given up 110 points.

Who will win tonight's Ragin' Cajuns/49ers college football game against the spread?

Guy's Pick: Take the Ragin' Cajuns -10.0

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