Mississippi State Bulldogs vs LSU Tigers Prediction, 10/17/2026 College Football Picks, Best Bets & Odds

Game: Mississippi State Bulldogs vs LSU Tigers

Date: Saturday, October 17, 2026

Location: Tiger Stadium in Baton Rouge, LA

TV: ESPN

Odds/Point Spread: Tigers (-13.5)

Total/Over-Under: 58.5

The Mississippi State Bulldogs (4-1) are hitting the road to Tiger Stadium on Saturday, October 17, 2026 where they will meet the LSU Tigers (4-2). LSU opens as 13.5-point favorites from oddsmakers. The over/under has been set at 58.5.

The Mississippi State Bulldogs head into this game 4-1 for this year. The last time they took the field, the Bulldogs took the field against the Missouri Tigers and notched a win by a score of 31-24. The Mississippi State Bulldogs ended up rushing 40 times and totaled 139 yds, which came out to an average of 3.5 yds per carry. Overall, they tallied 78 plays which gave them a total of 499 yds. Mississippi State allowed 23 completions on 40 tries for 295 yards, and a completion rate of 57.5%. On the ground, the Bulldogs gave up 119 yds on 35 attempts, which is 3.4 yds per run allowed.

The Bulldogs have earned 2,435 total yards for this campaign. In terms of distribution of touchdowns, Mississippi State has compiled 18 passing touchdowns and 7 rushing touchdowns. They have given the ball to the opposition 7 different times. Mississippi State has compiled 130 1st downs offensively, and they have been hurt by 40 infractions for 349 yds. Offensively they maintain an average of 177.8 yards in the run game giving them a rank of 54th in college football. Concerning getting in the endzone, the Mississippi State Bulldogs are averaging 39.0 points per game.

The Bulldogs rank 109th in college football regarding team defense, allowing 28.0 points per game. Opposing teams are running for an average of 3.6 yards per rush on the ground and 119.6 rushing yards per game on the campaign. Over the course of this season, they have conceded 598 running yards through 5 outings. When it comes to yards through the air, the Bulldogs have allowed 1,300 yards which puts them in 96th in the nation. They have surrendered 260.0 yards per game through the air as well as giving up a completion percentage of 62.8%. In total, they have given up 379.6 yards per outing putting them at 96th in the nation. They have yielded 9 touchdowns via the pass and 5 touchdowns pounding the rock.

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The Tigers come into this game with a record of 4-2 for this year. In their last game, the Tigers walked away with a victory by a final of 63-14 against the McNeese State Cowboys. LSU ended up running for 6.9 yards per tote, totaling 366 yds on 53 attempts. The Tigers finished the contest with 731 yards while running 101 plays (7.2 yds per play). The Tigers passing defense conceded a completion percentage of 47.1%, surrendering 94 yards on 8 for 17 through the air. LSU allowed 30 run attempts for 102 yards (3.4 yds per rush).

The LSU Tigers are averaging 524.8 yards per outing, which ranks them 4th in the nation. The LSU offense has racked up 306 penalty yards on 38 infractions, which is good for 60th in the country in terms of making mistakes. They hold an average of 213.7 run yards per game and have run for 1,282 yards for this year. They have tossed 8 picks while losing 2 fumbles and they have earned 167 first downs. Regarding putting points on the board, the Tigers currently sit 9th in the country scoring 42.0 points per contest. During the season to this point, the Tigers have thrown for a total of 1,867 passing yards along with holding an average of 311.2 passing yards per game, which ranks 8th in college football.

LSU has given up a total of 447 yards rushing (74.5 yards/game) and 7 touchdowns via the rush on the year. They have allowed 4 touchdowns through the air as well as 176.2 yards/contest, which has them ranked 30th in college football. Overall, they have surrendered 111 total points. They have tallied 2 fumbles recovered and 6 interceptions for the year. The Tigers defense has taken part in 351 plays, which ranks 47th in the country. The Tigers are giving up 18.5 points per contest, which has them sitting 33rd in the nation.

Who will win tonight's Bulldogs/Tigers college football game against the spread?

Josh's Pick: Take the Tigers -13.5

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