Mississippi State Bulldogs vs South Carolina Gamecocks Prediction, 9/19/2026 College Football Picks, Best Bets & Odds

Game: Mississippi State Bulldogs vs South Carolina Gamecocks

Date: Saturday, September 19, 2026

Location: Williams-Brice Stadium in Columbia, SC

TV: ESPN+

Odds/Point Spread: Gamecocks (-3.5)

Total/Over-Under: 58

The South Carolina Gamecocks (2-0) will take on the Mississippi State Bulldogs (2-0) at Williams-Brice Stadium on Saturday, September 19, 2026. Mississippi State opens this contest as 3.5-point underdogs. The total is set at 58.

The Mississippi State Bulldogs head into this game 2-0 for this season. In their last contest, the Bulldogs played the Minnesota Golden Gophers and went home with a win by a final score of 38-13. When it came to stopping the run, the Bulldogs gave up 13 yards on 15 tries, which averages out to 0.9 yds per rush allowed. Mississippi State allowed 31 pass completions on 48 attempts for a total of 279 yds, and a completion rate of 64.6%. In the game, they ran 68 plays which converted into 479 yds. The Mississippi State Bulldogs ran the rock 46 times and recorded 252 yds, which had them averaging 5.5 yds per attempt.

Concerning putting points on the board, the Mississippi State Bulldogs hold an average of 50.0 points per outing. As a team they're averaging 298.5 yards in the run game ranking them 9th in college football. The Bulldogs have earned 1,241 total yards for this campaign. When it comes to scoring, Mississippi State has amassed 7 touchdowns via the pass and 6 touchdowns on the ground. Mississippi State has accumulated 63 first downs, and they have been called for 14 penalties for 138 yds. They have given the ball to the opposition 1 time.

When talking about passing yardage, the Bulldogs have given up 419 yards which puts them in 72nd in the country. They are allowing 209.5 yards per game through the air as well as conceding a completion percentage of 61.8%. Over the course of this season, they are surrendering 285.0 yards per outing which ranks them 48th in the country. They have conceded 1 touchdown by air in addition to no TD's via the ground game. The opposition is running for 2.7 yards per rush and 75.5 rushing yards per contest so far this season. During the season, they have given up 151 running yards through 2 contests. The Bulldogs are ranked 34th in Division 1 when it comes to team defense, giving up 13.0 points per game.

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The Gamecocks come into this matchup with a record of 2-0 this season. When they last stepped on the field, the Gamecocks got the victory with a final of 45-9 when they played the Towson Tigers. The Gamecocks finished the contest with 502 yards on 67 plays (7.5 yds per play). South Carolina rushed for 9.9 yds per attempt, totaling 405 yards on 41 carries. South Carolina conceded 29 rush attempts for 21 yards (0.7 yds per rush). The Gamecocks secondary allowed a completion rate of 52.9%, surrendering 182 yards on 18 out of 34 through the air.

The South Carolina Gamecocks maintain an average of 573.5 yards per outing, which ranks them 5th in Division 1. The South Carolina offense has compiled 75 yards of penalties on 9 violations, which is good for 108th in college football in terms of making mistakes. They average 341.5 yards per game via the ground game and have run for 683 yards for the year. They have tossed 1 interception while losing 1 fumble and they have been able to obtain 57 first downs. When looking at their scoring prowess, the Gamecocks are sitting 12th in college football averaging 51.0 PPG. Over the course of the season to this point, the Gamecocks have thrown for 464 passing yards as well as holding an average of 232.0 throwing yards per game, which ranks 65th in D-1.

South Carolina has given up a total of 121 rushing yards (60.5 yards/game) as well as 0 touchdown via the rush for the campaign. They have conceded 1 touchdown via the pass and 130.5 yards/outing, which puts them in 18th in D-1. They have compiled no fumbles and 1 interception this year. The Gamecocks defense has been on the field for 111 plays, which is 23rd in the nation. The Gamecocks are surrendering 4.5 points per contest, which puts them 2nd in the nation.

Who will win tonight's Bulldogs/Gamecocks college football game against the spread?

Josh's Pick: Take the Gamecocks -3.5

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