Missouri Tigers vs Ole Miss Rebels Prediction, 10/17/2026 College Football Picks, Best Bets & Odds

Game: Missouri Tigers vs Ole Miss Rebels

Date: Saturday, October 17, 2026

Location: Vaught-Hemingway Stadium in Oxford, MS

TV: SEC Network

Odds/Point Spread: Rebels (-6.5)

Total/Over-Under: 59

The Missouri Tigers (5-1) are headed to Vaught-Hemingway Stadium on Saturday, October 17, 2026 where they will go up against the Ole Miss Rebels (4-1). Missouri opens this contest as 6.5-point dogs. The over/under is set at 59.

The Missouri Tigers step onto the field holding a record of 5-1 this year. In their last game, the Tigers faced off with the Texas A&M Aggies and earned the victory with a final of 27-6. When the final whistle blew, they ran 72 plays which converted into 394 yards. The Missouri Tigers ran the ball a total of 44 times and accrued 247 yds, which is an average of 5.6 yards per tote. On the ground, the Tigers conceded 27 yards on 23 tries, which is 1.2 yards per rush surrendered. Missouri surrendered 19 pass completions on 39 tries for a total of 189 yards, and a completion percentage of 48.7%.

The Tigers have earned 2,629 total yards over the course of this year. When it comes to distribution of touchdowns, Missouri has compiled 14 touchdowns through the air and 11 rushing touchdowns. They have surrendered the football 3 different times. Missouri has accrued 134 first downs offensively, and they have been called for 41 penalties for 387 yds. As a unit they are averaging 181.7 yards on the ground which ranks them 48th in college football. Regarding getting in the endzone, the Missouri Tigers are sitting at 35.8 PPG.

The Tigers are ranked 29th in the nation in terms of team defense, giving up 17.7 PPG. They are giving up 2.4 yards per rushing attempt and 78.3 yards on the ground per game so far this season. Over the course of this year, they have allowed 470 running yards through 6 outings. When talking about passing yards, the Tigers have conceded 1,345 yards which puts them in 104th in the nation. They are allowing 224.2 yards per game via the pass and giving up a completion percentage of 56.8%. In total, they are surrendering 302.5 yards/game ranking them 29th in Division 1. They have surrendered 10 touchdowns through the air and 2 touchdowns pounding the rock.

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The Rebels head into this game 4-1 for this season. When they last stepped on the field, the Rebels walked away with a victory by a final of 52-17 against the Vanderbilt Commodores. Ole Miss conceded 37 rush attempts for 103 yards (2.8 yards per carry). The Rebels pass defense conceded a completion percentage of 56.8%, relinquishing 240 yards on 21 for 37 passing. The Rebels finished the contest with 409 yards while they ran 65 plays (6.3 yds per play). Ole Miss ran the ball for 5.6 yards per attempt, totaling 196 yards on 35 carries.

Regarding their scoring prowess, the Rebels sit 21st in college football holding an average of 38.8 PPG. The Ole Miss Rebels hold an average of 433.8 yards per game, which ranks them 43rd in Division 1. The Ole Miss offense has totaled 328 penalty yards on 40 infractions, which is good for 49th in the country in terms of hurting your team. They have thrown 5 interceptions while letting opponents recover 2 fumbles and they have been able to obtain 121 first downs. During this campaign thus far, the Rebels currently have a total of 1,503 yards via the pass as well as holding an average of 300.6 passing yards per outing, ranking them 15th in Division 1. They have an average of 133.2 yards via the ground game and have run for 666 yards overall.

The Rebels are conceding 28.0 PPG, which puts them 108th in the nation. Ole Miss has allowed a total of 882 yards via the ground game (176.4 yards per game) in addition to 11 touchdowns on the ground on the year. They have allowed 5 touchdowns through the air and 216.0 yards/game, which has them in 82nd in Division 1. The Rebels defense has participated in 349 plays, which ranks 46th in Division 1. Their defense has compiled 2 fumbles recovered and 4 interceptions for the season. Overall, they have relinquished 140 points.

Who will win tonight's Tigers/Rebels college football game against the spread?

Tony's Pick: Take the Tigers +6.5

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