Syracuse Orange vs Virginia Cavaliers Prediction, 10/10/2026 College Football Picks, Best Bets & Odds

Game: Syracuse Orange vs Virginia Cavaliers

Date: Saturday, October 10, 2026

Location: Scott Stadium in Charlottesville, VA

TV: ACC Network

Odds/Point Spread: Cavaliers (-9.5)

Total/Over-Under: 49.5

Scott Stadium is the site where the Virginia Cavaliers (3-2) will attempt to beat the Syracuse Orange (2-2) on Saturday, October 10, 2026. Virginia is 9.5-point favorites. The betting total comes in at 49.5.

The Syracuse Orange come into this game with a record of 2-2 for this season. In their last game, the Orange faced the Connecticut Huskies and notched a win by a score of 42-41. When the final whistle blew, they had 85 plays which totaled 509 yds. The Syracuse Orange ended up running the ball 48 different times and accumulated 174 yards, which earned them an average of 3.6 yds per attempt. When it came to stopping the run, the Orange gave up 181 yards on 34 attempts, which averages out to 5.3 yards per run allowed. Syracuse conceded 20 completions on 40 tries for a total of 318 yards, and a completion rate of 50.0%.

The Orange have racked up 1,807 total yards for the season. When it comes to getting the ball in the endzone, Syracuse has compiled 10 passing touchdowns and 7 touchdowns on the ground. They have turned the ball over 7 times. Syracuse has 111 1st downs as a team, and they have committed 44 penalties for 413 yards. As a team they are averaging 166.5 yards on the ground ranking this team at 62nd in Division 1. Concerning scoring, the Syracuse Orange have an average of 34.8 points per contest.

Regarding yards through the air, the Orange have allowed 722 yards which puts them in 15th in the nation. They have relinquished 180.5 yards per contest via the pass as well as conceding a completion percentage of 53.6%. During this campaign, they have yielded 318.8 yards per game putting them 46th in college football. They have granted 5 touchdowns through the air and 6 touchdowns on the ground. They are giving up 4.2 yards per rushing attempt and 138.3 yards on the ground per game for the year. In total, they have allowed 553 yards via the running game in 4 games. The Orange are ranked 63rd in the country when it comes to team defense, giving up 23.0 PPG.

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The Cavaliers head into this matchup 3-2 for this year. In their last game, the Cavaliers went home defeated by a final of 38-7 against the Florida State Seminoles. Virginia ran the ball for 0.9 yds per attempt, finishing with 37 yards on 40 carries. The Cavaliers finished with a total of 205 yds and they ran 72 plays (2.8 yards per play). The Cavaliers secondary gave up a completion rate of 63.2%, relinquishing 183 yds on 12 for 19 passing. Virginia allowed 46 attempts on the ground for 281 yds (6.1 yds per rush).

Concerning the points being put on the board, the Cavaliers rank 52nd in the nation holding an average of 33.8 points per outing. The Virginia Cavaliers maintain an average of 398.8 yards/game, which is good for 65th in Division 1. The Virginia offense has accrued 245 penalty yds on 27 infractions, which is 100th in the country in terms of giving up free yards. They have given away 1 interception while surrendering 1 fumble and they have been able to obtain 115 first downs. For the season thus far, the Cavaliers have compiled 1,186 yards through the air as well as an average of 237.2 passing yards per contest, which has them ranked 63rd in D-1. They are averaging 161.6 yards per game on the ground and have toted the ball for 808 yards in total.

Virginia has given up a total of 748 rushing yards (149.6 yards per game) and 9 touchdowns by way of the ground game on the season. They have surrendered 2 touchdowns via the pass and 140.8 yards/game, which has them ranked 6th in Division 1. This year, they have given up 90 total points. They have compiled 1 fumble recovery and 7 interceptions on the year. The Cavaliers defense has been on the field for 306 plays, which ranks 60th in D-1. The Cavaliers are relinquishing 18.0 points per game, which puts them 35th in Division 1.

Who will win tonight's Orange/Cavaliers college football game against the spread?

Guy's Pick: Take the Cavaliers -9.5

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