USC Trojans vs Penn State Nittany Lions Prediction, 10/10/2026 College Football Picks, Best Bets & Odds

Game: USC Trojans vs Penn State Nittany Lions

Date: Saturday, October 10, 2026

Location: Beaver Stadium in University Park, PA

TV: NBC

Odds/Point Spread: Nittany Lions (-1.5)

Total/Over-Under: 54.5

The USC Trojans (5-1) are en route to Beaver Stadium on Saturday, October 10, 2026 where they will attempt to beat the Penn State Nittany Lions (3-2). USC opens this game as 1.5-point underdogs. The total is 54.5.

The USC Trojans come into this game with a record of 5-1 for this year. In their last game, the Trojans faced the Washington Huskies and went home with a win by a final score of 25-21. On the day, they ran 69 plays which gave them a total of 360 yards. The USC Trojans ran the ball 35 times and amassed 115 yards, which came out to an average of 3.3 yards per attempt. When it came to stopping the run, the Trojans gave up 116 yds on 33 attempts, which averages out to 3.5 yards per run allowed. USC surrendered 16 completions on 27 tries for a total of 203 yards, and a completion percentage of 59.3%.

When talking about getting in the endzone, the USC Trojans have an average of 37.3 PPG. As a team they're averaging 156.2 yards on the ground which is 74th in college football. The Trojans have earned 2,807 total yards for this campaign. When it comes to getting the ball in the endzone, USC has totaled 15 touchdowns through the air and 11 touchdowns via the ground. USC has amassed 152 first downs offensively, and they have been flagged for 41 penalties for 365 yds. They have surrendered the football 6 different times.

In terms of passing yards, the Trojans have given up 1,384 yards which ranks them 132nd in D-1. They have conceded 230.7 yards per game via the pass and giving up a completion percentage of 63.2%. In total, they have relinquished 348.8 yards/outing which puts them 68th in Division 1. They have given up 10 touchdowns via the pass and 10 touchdowns via the ground game. The opposition is running for 3.9 yards per rush and 118.2 rushing yards per contest for the season. In total, they have allowed 709 rushing yards through 6 games. The Trojans are ranked 89th in the country concerning team defense, allowing 25.5 PPG.

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The Nittany Lions head into this game 3-2 for this season. When they last stepped on the field, the Nittany Lions took a defeat with a final score of 34-13 when they played the Northwestern Wildcats. Penn State gave up 55 running attempts for 413 yards (7.5 yds per rush). The Nittany Lions secondary allowed a completion percentage of 71.4%, surrendering 93 yds on 10 out of 14 through the air. The Nittany Lions finished the contest with 291 yds and they ran 63 plays (4.6 yards per play). Penn State rushed for 2.2 yards per attempt, totaling 48 yards on 22 carries.

Concerning the points being put on the board, the Nittany Lions currently sit 63rd in Division 1 with 32.0 points per game. The Penn State Nittany Lions are averaging 400.0 yards per game, which has them ranked 63rd in the country. The Penn State offense has racked up 236 yds of penalties on 24 infractions, which is good for 116th in D-1 in terms of helping out the opposition. They have thrown 3 interceptions while allowing opponents to recover no fumbles and they have been able to obtain 105 1st downs. During this campaign thus far, the Nittany Lions have earned 1,218 passing yards together with an average of 243.6 throwing yards per game, which has them sitting 57th in college football. They are averaging 156.4 rushing yards per game and have toted the ball for 782 yards in total.

Penn State has given up a total of 866 rushing yards (173.2 yards per outing) and 7 touchdowns via the rush this season. They have given up 2 touchdowns via the pass in addition to 119.6 yards per outing, ranking them 3rd in college football. This year, they have surrendered 80 points in total. They have earned 4 fumbles recovered and 5 interceptions so far this year. The Nittany Lions defense has taken part in 307 plays, which ranks 63rd in D-1. The Nittany Lions are conceding 16.0 PPG, which has them ranked 25th in the country.

Who will win tonight's Trojans/Nittany Lions college football game against the spread?

Tony's Pick: Take the Nittany Lions -1.5

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