Detroit Pistons vs Chicago Bulls Prediction, 10/22/2025 Preview and Pick
Game: Detroit Pistons vs Chicago Bulls
Date: Wednesday, October 22, 2025
Location: United Center in Chicago, IL
TV: CHSN
Odds/Point Spread: Detroit (-3.5)
United Center is the site where the Chicago Bulls (39-43 last season) will try to defeat the Detroit Pistons (44-38 last year) on Wednesday. Chicago is 3.5-point dogs. The over/under is set at 232.5.

The Pistons stepped onto the hardwood against the Knicks and took a loss by a final of 116-113 in their last game. Regarding personal fouls, the Pistons ended up with 23 while the Knicks recorded 22 personal fouls. They made 10 of their 30 attempts from three-point range. New York finished the game at 80.0% from the free throw line by making 24 of 30 tries. On top of that, New York had 43 boards (13 offensive, 30 defensive) and got 3 blocks. New York recorded 18 assists and had 6 steals in this game. Pertaining to defense, Detroit allowed the other team to shoot 47.7% from the floor on 41 out of 86 shooting. They also dished out 25 assists for the contest in addition to forcing 17 turnovers and having 9 steals. In reference to hauling in boards, they earned 36 with 6 of them being on the offensive end. From the charity stripe, the Pistons buried 28 of 33 attempts for a percentage of 84.8%. Detroit ended the contest with a 46.9% field goal percentage (38 of 81) and made 9 of their 34 three-point shots.
Cade Cunningham is one player who was a major factor in the matchup. Cunningham finished the game at 40.9% from the floor and earned 8 dimes. He played for 44 minutes played and pulled down 7 boards. He recorded 23 points on 9 out of 22 shooting.
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Detroit comes into this contest after finishing with a mark of 44-38 last year. They coughed up possession 14.9 times per contest and as a team committed 20.7 fouls per contest. As a group, Detroit snagged 44.8 rebounds per contest and had 2,165 assists throughout last year, which was 15th in basketball in terms of passing the rock. The Pistons hit on 36.2% on shots beyond the perimeter (1,051 of 2,901) and 77.4% from the charity stripe. They averaged 115.5 points per outing (12th in the league) while hitting 47.6% from the field.
Defensively, the Pistons forced 15.1 turnovers per contest while drawing 18.9 fouls. They gave up 36.6% on shots from downtown and they ranked 14th in basketball in points per game allowed (113.6). The Pistons gave up a shooting percentage of 46.1% (3,326 of 7,210) and they conceded 42.5 boards per contest as a team. They were ranked 6th in the league in giving up assists to their opponents with 2,035 surrendered last season.
The last time they took the court, the Bulls walked away with a victory by a final of 122-102 when they faced the 76ers. When talking about team rebounding, Chicago allowed Philadelphia to collect 48 overall (10 on the offensive side). They finished 27.3% from beyond the perimeter by hitting 12 of 44 and ended up shooting 18 out of 21 at the free throw line (85.7%). The Bulls allowed the 76ers to bury 36 of 94 attempts from the field which left them with a shooting percentage of 38.3% for the matchup. Overall, the Bulls ended up going 47 for 103 from the floor which gave them a shooting percentage of 45.6%. When talking about three-point shots, Chicago knocked down 13 out of 40 tries (32.5%). They were able to knock down 15 of the free throw tries for a rate of 75.0%. The 76ers committed 15 fouls in this game which got the Bulls to the charity stripe for a total of 20 tries. They also turned it over 13 times, while getting 10 steals in the game. The Bulls pulled down 44 defensive boards and 15 offensive boards for a total of 59 for the game.
Kevin Huerter ended up being a factor for the Bulls for the game. He converted 6 of 11 in this contest giving him a field goal percentage of 54.5%, and accumulated 2 rebounds. Huerter earned 18 points in his 16 mins on the hardwood and accounted for 2 assists in this matchup.
Chicago had a mark of 39-43 last year. As an offense, the Bulls shot 47.0% from the floor, which ranked them 15th in the league. Chicago earned 9,660 points last year (117.8 per game) and they grabbed 45.9 boards per contest. They dished out assists 29.1 times per contest (5th in the league) and they lost possession via turnover 14.7 times per game. The Bulls were responsible for committing 17.6 personal fouls per game and they shot 80.9% from the charity stripe.
The Chicago defense conceded 34.4% on shots from behind the 3-point line (1,118 of 3,250) and their opponents converted on 78.6% of their free throw shots. They gave up 28.9 dimes and 46.1 boards per contest, which ranked them 28th and 28th in basketball. The Bulls defensively were ranked 28th in basketball in PPG given up with 119.4. They forced 12.6 turnovers per game and allowed teams to shoot 46.7% from the field (16th in the league).
Who will win tonight's NBA game against the spread?
Guy Bruhn's Pick: Take Chicago (+3.5)
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Additional Resources:
Chicago Bulls - Twitter
Detroit Pistons - Twitter