San Antonio Spurs vs Los Angeles Lakers Prediction, 12/10/2025 Preview and Pick
Game: San Antonio Spurs vs Los Angeles Lakers
Date: Wednesday, December 10, 2025
Location: crypto.com Arena in Los Angeles, CA
TV: Prime Video
Odds/Point Spread: San Antonio (+4.5)
The Los Angeles Lakers (17-6) will take on the San Antonio Spurs (16-7) at crypto.com Arena on Wednesday in the NBA Cup quarterfinals. San Antonio is 4.5-point dogs. The betting total comes in at 235.

The Spurs stepped onto the hardwood against the Pelicans and went home with a win by a final score of 135-132 in their last game. In reference to fouls, the Spurs ended up with 19 while the Pelicans finished the game with 23 fouls. They also made 7 out of their 26 attempts from distance. New Orleans finished the game shooting 88.5% from the free throw line by converting 23 of their 26 attempts. Additionally, New Orleans grabbed 33 rebounds (4 offensive, 29 defensive), but finished the game with no rejections. New Orleans recorded 35 dimes and had 8 steals in this game. In relation to the defense, San Antonio allowed the other team to go 58.0% from the field on 51 of 88 shooting. They also doled out 29 assists in this contest in addition to forcing the other team into 9 turnovers and earning 5 steals. Regarding hauling in rebounds, they compiled 44 with 13 of them being offensive. At the charity stripe, the Spurs knocked down 20 of their 25 attempts for a percentage of 80.0%. San Antonio finished the game with a 49.5% field goal percentage (49 out of 99) and made 17 out of their 36 shots from beyond the arc.
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Harrison Barnes is one player who was a factor in this matchup. He notched 24 points on 9 of 15 shooting. He played for 35 minutes and totaled 2 rebounds. Barnes shot 60.0% from the field and totaled 1 assist.
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San Antonio heads into this matchup with a mark of 16-7 on the campaign. They have an average of 119.6 points per game (7th in the league) while going 48.5% from the field. The Spurs are shooting 36.6% on shots beyond the perimeter (309 of 845) and 79.6% from the free throw line. As a team, San Antonio is pulling in 44.6 rebounds per game and has earned 597 dimes on the year, which is 21st in the league in terms of passing. They are giving up possession 14.8 times per contest and as a team they are committing 20.7 fouls per contest.
Defensively, the Spurs are forcing their opponents into 14.4 turnovers per contest and they draw 22.0 fouls. They concede 38.0% on 3-pointers and they are ranked 11th in the league in points per game allowed (115.3). The Spurs defensively are allowing a shooting percentage of 47.1% (965 of 2,048) and they surrender 41.0 rebounds per game as a team. They are ranked 11th in the league in giving up assists to the opposition with 627 conceded on the season.
When they last stepped on the court, the Lakers took home the win by a final score of 112-108 against the 76ers. Concerning how they cleaned up the glass, Los Angeles permitted Philadelphia to snag 54 in all (17 offensive). They shot 36.1% from distance by shooting 13 of 36 and finished the contest at 23 of 26 from the free throw line (88.5%). The Lakers allowed the 76ers to knock down 36 out of 102 attempts from the floor which had them shooting 35.3% in this contest. Overall, the Lakers finished 41 for 85 from the floor which gave them a rate of 48.2%. Regarding shots from beyond the perimeter, Los Angeles buried 13 of their 36 tries (36.1%). They were able to knock down 17 of the free throw attempts for a rate of 63.0%. The 76ers were called for 17 fouls for the game which got the Lakers to the charity stripe for 27 shots. They also turned it over 10 times, while getting 3 steals in this game. The Lakers were able to corral 44 defensive rebounds and 8 offensive rebounds totaling 52 in the game.
Luka Doncic was important for the Lakers in this contest. He made 9 of 24 in the game for a rate of 37.5%, and added 15 rebounds. Doncic tallied 31 points in his 39 minutes on the court and totaled 11 dimes in the game.
Los Angeles has a mark of 17-6 so far this year. As an offense, the Lakers are shooting 50.7% from the floor, which is 2nd in the league. Los Angeles has totaled 2,721 pts so far this season (118.3 per game) and they snag 41.0 boards per game. Their rate of dishing out assists is at 25.2 times per contest (24th in the NBA) and they turn the ball over 15.7 times per game. The Lakers commit 19.3 fouls every game and they connect on 79.8% from the free throw line.
The Lakers are ranked 16th in basketball in points per game surrendered with 116.1. They are forcing 15.0 turnovers per game and allow teams to shoot 48.0% from the field (24th in the league). The Los Angeles defense surrenders 37.9% on shots from behind the 3-point line (329 of 867) and opponents are converting on 80.4% of their free throw attempts. They surrender 27.6 dimes and 39.6 rebounds on a nightly basis, which is ranked 24th and 2nd in basketball.
Who will win tonight's NBA game against the spread?
Guy Bruhn's Pick: Take Los Angeles (-4.5)
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Additional Resources:
Los Angeles Lakers - Twitter
San Antonio Spurs - Twitter

