Portland Trail Blazers vs San Antonio Spurs Prediction, 4/21/2026 Preview and Pick

Game: Portland Trail Blazers vs San Antonio Spurs

Date: Tuesday, April 21, 2026

Location: Frost Bank Center in San Antonio, TX

TV: Peacock

Odds/Point Spread: Portland (+11.0)

Frost Bank Center is the site where the San Antonio Spurs (62-20) will compete against the Portland Trail Blazers (42-40) on Tuesday in Game 2 of their series. San Antonio leads the series 1-0. Portland opens this contest as 11.0-point dogs. The betting total is set at 219.

The Trail Blazers took a loss by a final of 111-98 in Game 1. When talking about fouls, the Trail Blazers ended up with 17 and the Spurs accumulated 19 fouls. They knocked down 15 out of their 33 tries from long range. San Antonio walked away from this one shooting 84.2% from the charity stripe by making 16 of their 19 shots. Furthermore, San Antonio grabbed 45 rebounds (11 offensive, 34 defensive) and earned 2 blocks. San Antonio earned 24 dimes and had 6 steals for the contest. Pertaining to defense, Portland let their opponent shoot 47.6% from the field on 40 of 84 shooting. They also recorded 28 dimes for the matchup in addition to creating 14 turnovers and having 9 steals. In reference to rebounding, they collected 38 with 8 of them being offensive. From the free throw line, the Trail Blazers converted 10 of 12 tries for a rate of 83.3%. Portland walked away from the contest having earned a 42.9% FG percentage (39 out of 91) and knocked down 10 out of their 38 three-point attempts.

Deni Avdija is someone who was a major factor for the matchup. He ended up walking away with 30 points on 12 of 21 shooting. He was on the hardwood for 39 minutes and also grabbed 10 rebounds. Avdija finished the game at 57.1% from the field and also earned 5 assists.

Get all of our NBA Picks Tonight

Portland steps onto the hardwood with a record of 42-40 on the year. They are turning it over 17.3 times per game and as a unit are committing 19.9 fouls per game. As a team, Portland is snagging 46.0 rebounds per contest and has accumulated 2,062 assists so far this year, which ranks 23rd in the league in terms of passing. The Trail Blazers are shooting 34.3% on three-point attempts (1,186 of 3,462) and 76.5% from the free throw line. They have an average of 115.5 points per game (17th in basketball) while shooting 45.3% from the floor.

When they are on defense, the Trail Blazers are forcing their opponents into 15.6 turnovers on a nightly basis and they draw 22.0 personal fouls. They are conceding 35.8% on shots from beyond the arc and they are 16th in the league in PPG from their opponents (115.8). The Trail Blazers are giving up a shooting percentage of 47.1% (3,446 of 7,323) and they concede 43.0 boards per game as a team. They rank 13th in the league in allowing assists to the opposition with 2,162 relinquished so far this year.

The Spurs dominated Game 1 in almost every category. In regard to how they rebounded, San Antonio permitted Portland to grab 38 overall (8 offensive). They finished 26.3% from 3-point land by going 10 out of 38 and finished the game at 10 of 12 from the charity stripe (83.3%). The Spurs allowed the Trail Blazers to make 39 out of 91 tries from the field which gave them a rate of 42.9% for the game. When the final whistle was blown, the Spurs shot 40 for 84 from the floor which had them shooting 47.6%. In reference to three-point attempts, San Antonio made 15 of their 33 attempts (45.5%). They were able to knock down 16 of those for a clip of 84.2%. The Trail Blazers committed 17 personal fouls in this game which took the Spurs to the free throw line for 19 attempts. They turned the ball over 14 times, while recording 6 steals for this contest. The Spurs were able to collect 34 defensive boards and 11 offensive boards for a total of 45 in this matchup.

Victor Wembanyama ended up having an impact for the Spurs for this contest. Wembanyama accumulated 35 points in his 33 minutes on the hardwood and accumulated 1 assist in this game. He converted 13 of 21 for the contest for a rate of 61.9%, and accumulated 5 rebounds.

San Antonio has a record of 62-20 on the year. The Spurs are committing 18.9 fouls every game and they hit 78.7% from the charity stripe. They are assisting teammates 28.1 times per game (9th in the league) and they lose possession via turnover 13.5 times per game. San Antonio has totaled 9,826 points so far this season (119.8 per game) and they pull in 47.0 rebounds per game. As an offense, the Spurs are hitting on 48.3% from the field, which ranks them 6th in basketball.

The San Antonio defense allows 35.2% from downtown (1,066 of 3,028) and their opposition makes 79.0% of their shots from the charity stripe. They concede 26.2 dimes and 42.6 boards on a nightly basis, which ranks them 12th and 8th in the NBA. The Spurs defensively are ranked 8th in the league in PPG surrendered with 111.5. They are forcing 13.0 TO's per game and allow teams to shoot 45.1% from the field (4th in basketball).

Who will win tonight's NBA game against the spread?

Guy Bruhn's Pick: Take San Antonio (-11.0)

Get $60 worth of FREE premium member picks. No Obligation. No Salesman. No Credit Card. Fast Sign up with Instant Access Click Here

Get NBA picks on every single game, or if you want our very best bets by the experts, sign up for your free $60 account with a guarantee.