Ottawa Senators vs Buffalo Sabres Prediction, 10/15/2025 NHL Picks, Best Bets & Odds

Game: Ottawa Senators vs Buffalo Sabres

Date: Wednesday, October 15, 2025

Location: KeyBank Center in Buffalo, NY

TV: MSG Network

Odds/Point Spread: Senators (-150) Sabres (+125)

KeyBank Center is the location where the Buffalo Sabres (0-3-0) will attempt to defeat the Ottawa Senators (1-2-0) on Wednesday. The moneyline on this game has the Senators at -150 and the Sabres open at +125. The over/under has been set at 6.

The Ottawa Senators were on the losing side of the ice with a 4-1 loss to the Predators their last time on the ice. Ottawa accrued 12 penalty mins in this contest. The Senators didn't have a great showing offensively in the defeat. Moreover, they had 5 power play attempts and were able to net 1 goal. In the game, they converted 1 of the 32 shots they attempted.

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Ottawa Senators opponents have earned 14 power play opportunities (6th in professional hockey) and have notched 5 goals in those chances. The Senators so far have had 78 shots tried against them and are the owners of a save percentage of .821. Ottawa has tried 94 shots and has a shooting percentage of 8.5%. When at even strength, the Senators have given up 9 goals while getting 6 when they are on offense. Ottawa comes into tonight with 11 power play chances and they have notched 2 goals out of those advantages, giving them a rate of 18.18%. For the current campaign, they have earned 2 points and their points percentage is .333. In regard to their scoring, the Ottawa Senators have earned 8 goals (23rd in the league) for the year and have allowed 14.

The man in net for this game is Linus Ullmark. Over the course of his time in hockey, Ullmark has tallied 180 quality starts and his quality starts percentage is .634. His save percentage is at .916 in his 16,762 mins on the ice. Ullmark has had 8,636 shots against him and has garnered 7,914 total saves. Opponents have been able to score 722 goals versus Ullmark in his pro hockey career and his goals against average per contest is 2.58. He has a mark of 164-89-26 and he has gotten the start in 284 games. Ullmark has been in goal for 294 contests over the course of his hockey career.

When they were on the ice last, Buffalo faced off against the Avalanche in an outing where the Sabres went home in defeat by a mark of 3-1. They had 3 power play opportunities in this one but weren't able to finish one of them with a goal. The Sabres scored 1 goal of the 29 shots on goal they took.

The Sabres have tallied 2 goals at even strength and 0 goals (32nd in pro hockey) while on the power play. Buffalo has attempted 88 shots (13th in the NHL) and has accumulated a shooting percentage of 2.27%, while allowing the other team 101 shots. On the campaign, the Buffalo Sabres have notched a total of 2 goals, 0 points, in addition to a points percentage of .000. They have permitted 10 goals to be scored by way of 10 goals at even strength and 0 goals while they had less men on the ice. They have recorded 11 power play chances and they have earned a power play percentage of 0.00%. They have earned a penalty kill rate of 100.00% on their oppositions 11 opportunities on the power play, and their save percentage sits at 90.1%.

On the other side of the ice you are going to see Alex Lyon between the pipes. Lyon holds a lifetime mark of 51-41-11 and has played in 116 games. Lyon's quality start rate is 52.4% and he has earned 54 quality starting assignments in his NHL career. He has racked up 2,875 stops out of 3,186 shots taken against him, giving him a percentage of .902. Teams are averaging 982.11 goals/game and he has given up 311 goals in total. He has started in 103 games and has been on the ice for 19 mins.

Who will win tonight's NHL game against the spread or moneyline?

Guy's Pick: Take Buffalo (+125)

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