Vegas Golden Knights vs St. Louis Blues Prediction, 10/22/2026 NHL Picks, Best Bets & Odds

Game: Vegas Golden Knights vs St. Louis Blues

Date: Thursday, October 22, 2026

Location: Enterprise Center in St. Louis, MO

TV: Vegas 34, Blue Note+

Odds/Point Spread: Golden Knights (-117) Blues (+100)

The Vegas Golden Knights (8-3-0) are on their way to Enterprise Center on Thursday where they will attempt to beat the St. Louis Blues (4-4-1). The odds on this game have the Golden Knights at -117 while the Blues are opening at +100. The betting total comes in at 6.5.

The Vegas Golden Knights will need a bounce back game after taking a 6-2 defeat to the Lightning in their previous contest . Vegas accrued 6 penalty minutes for this matchup. Additionally, they had 4 chances with the advantage but weren't able to make the most of them. The Golden Knights had a below average offensive performance in the loss. For the matchup, they converted 2 of the 34 shots they launched.

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When playing at even strength, the Golden Knights have surrendered 23 goals while scoring 33 themselves. Vegas Golden Knights opponents have totaled 26 power play opportunities (26th in the league) and have scored 7 goals in those chances. When it comes to scoring goals, the Vegas Golden Knights have racked up 43 goals (1st in the league) this season and have given up 30. Vegas has tried 332 shots and holds a shot percentage of 13.0%. For the season, they have recorded 16 points and their points percentage is sitting at .727. The Golden Knights have had 275 shots taken against them and hold a save percentage of .891. Vegas has accumulated 40 power play chances and they have scored 10 goals during those advantages, giving them a percentage of 25.00%.

The player between the pipes for this game is Carter Hart. The opposition has notched 691 goals against Hart in his pro career and his goals against average per game is 2.84. Hart has played in 252 matchups during his NHL career. His save percentage is at .904 for his 13,787 minutes guarding the cage. He has amassed an overall mark of 111-99-32 and he was named the starter in 243 games. Over the course of his career, Hart is sitting with 121 quality starts and his quality starts percentage is .498. Hart has had 7,230 shots against him and has amassed 6,539 saves.

In their last game, St. Louis faced off against the Jets in a matchup where the Blues notched a victory by a mark of 2-1. The Blues scored 2 goals of the 28 shots on goal they tried. They had 5 power play chances in this contest and converted 1 out of those tries.

St. Louis has put up 236 shots (21st in the NHL) and has earned a shot percentage of 12.29%, while allowing the opposition 246 shots. They have a penalty kill rate of 85.71% on the other teams 28 power play chances, and their save percentage sits at 88.2%. They have earned 26 power play opportunities and they have a power play percentage of 19.23%. The Blues are sitting with 24 goals at even strength and 5 goals (23rd in the NHL) while on the power play. They have allowed 29 goals to be scored by way of 25 goals at even strength and 4 goals while they were shorthanded. For the year, the St. Louis Blues have a total of 29 goals, 9 points, and a points percentage of .500.

Across the ice you are likely to see Joel Hofer in net. Hofer has amassed a career record of 62-37-11 and has been in net for 121 games. Hofer's rate of quality starts comes out to 59.8% and he has qualified for 67 quality starting assignments in his pro hockey career. He is sitting with 2,943 saves out of the 3,237 shots taken against him, giving him a save percentage of .909. Opponents are averaging 2.64 goals per game and he has allowed 296 goals altogether. He has started in 112 games and has played for a total of 280 mins.

Who will win tonight's NHL game against the spread or moneyline?

Tony's Pick: Take Vegas (-117)

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