Bowling Green Falcons vs Louisville Cardinals Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

Game: Bowling Green Falcons vs Louisville Cardinals

Date: Saturday, September 20, 2025

Location: L&N Federal Credit Union Stadium in Louisville, KY

TV: ACC Network

Odds/Point Spread: Cardinals (-26.5)

Total/Over-Under: 51.5

L&N Federal Credit Union Stadium is the location where the Louisville Cardinals (2-0) will attempt to beat the Bowling Green Falcons (2-1) on Saturday, September 20, 2025. Louisville opens as 26.5-point favorites. The betting total is set at 51.5.

The Bowling Green Falcons head into this game 2-1 for this year. The last time they stepped onto the field, the Falcons faced the Liberty Flames and earned the victory with a final of 23-13. The Bowling Green Falcons ended up rushing 36 different times and totaled 158 yards, which earned them an average of 4.4 yds per attempt. In all, they ran 68 plays which converted into 304 yds. Bowling Green gave up 13 completions on 25 attempts for 194 yds, and a completion rate of 52.0%. In the running game, the Falcons conceded 152 yds on 39 tries, which is 3.9 yards per rush allowed.

In terms of scoring, the Bowling Green Falcons have an average of 23.0 points per game. Offensively they hold an average of 137.7 yards in the run game which is 89th in Division 1. The Falcons have attained 942 total yards this season. When it comes to getting in the endzone, Bowling Green has totaled 2 touchdowns via the pass and 3 touchdowns on the ground. Bowling Green has compiled 55 1st downs as a team, and they have been flagged for 21 penalties for 171 yards. They haven't turned the ball over yet.

Concerning yards through the air, the Falcons have allowed 645 yards which has them sitting in 82nd in the country. They have relinquished 215.0 yards per contest through the air as well as allowing a completion percentage of 58.8%. During the season, they have surrendered 320.7 yards/game ranking them 60th in the country. They have conceded 5 touchdowns via the pass in addition to 2 touchdowns via the ground game. They are allowing an average of 3.2 yards per attempt on the ground and 105.7 rushing yards per contest so far this year. Over the course of this season, they have conceded 317 yards via the ground game in 3 contests. The Falcons are ranked 47th in college football when it comes to team defense, allowing 18.0 points per contest.

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The Cardinals come into this game with a record of 2-0 for this year. When they last played, the Cardinals walked away with a victory by a final of 28-14 against the James Madison Dukes. Louisville ran the ball for 3.8 yards per carry, finishing the contest with 113 yds on 30 attempts. The Cardinals finished with a total of 264 yds while they ran 53 plays (5.0 yards per play). The Cardinals pass defense conceded a completion rate of 58.1%, surrendering 137 yds on 18 out of 31 passing. Louisville allowed 47 attempts on the ground for 126 yds (2.7 yds per carry).

When it comes to their scoring prowess, the Cardinals sit 35th in Division 1 with 39.5 points per game. The Louisville Cardinals are averaging 403.0 yards/game, which has them sitting 63rd in D-1. The Louisville offense has totaled 155 yards of penalties on 17 violations, which ranks 73rd in the nation in terms of giving up free yards. They have tossed 3 interceptions while surrendering 1 fumble and they have earned 40 1st downs. During the season to this point, the Cardinals have a total of 464 yards via the pass not to mention holding an average of 232.0 passing yards per contest, which ranks 66th in the country. They average 171.0 yards per game via the rush and have rushed for 342 yards for the year.

Louisville has yielded a total of 200 rushing yards (100.0 yards per outing) as well as 2 touchdowns by way of the ground game so far this year. They have allowed the opposition 1 touchdown from the passing game and 106.5 yards per game, which has them in 7th in the nation. Overall, they have given up 31 total points. They have totaled 1 fumble recovery and 1 pick on the campaign. The Cardinals defense has been on the field for 131 plays, which ranks them 14th in the nation. The Cardinals are relinquishing 15.5 points per game, ranking them 37th in the country.

Who will win tonight's Falcons/Cardinals college football game against the spread?

Josh's Pick: Take the Falcons +26.5

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