Clemson Tigers vs Boston College Eagles Prediction, 10/11/2025 College Football Picks, Best Bets & Odds
Game: Clemson Tigers vs Boston College Eagles
Date: Saturday, October 11, 2025
Location: Alumni Stadium in Chestnut Hill, MA
TV: ACC Network
Odds/Point Spread: Eagles (+14.0)
Total/Over-Under: 55
The Clemson Tigers (2-3) are headed to Alumni Stadium on Saturday, October 11, 2025 where they will meet the Boston College Eagles (1-4). Clemson opens as 14.0-point favorites. The total has been set at 55.
The Clemson Tigers step onto the field holding a record of 2-3 for this season. The last time they stepped onto the field, the Tigers stepped onto the field against the North Carolina Tar Heels and earned the victory with a final of 38-10. The Clemson Tigers ran the rock 31 times and tallied 89 yds, earning them an average of 2.9 yds per attempt. In all, they ran 70 plays which gave them a total of 488 yds. Clemson allowed 26 completions on 42 attempts for a total of 213 yards, and a completion rate of 61.9%. Against the run, the Tigers conceded 57 yds on 18 attempts, which averages out to 3.2 yards per run surrendered.

The Tigers have tallied 1,949 total yards over the course of this year. In terms of getting in the endzone, Clemson has amassed 11 touchdowns via the pass and 4 touchdowns on the ground. They have surrendered the ball 8 different times. Clemson has tallied 99 1st downs offensively, and they have been flagged for 26 infractions for 272 yards. As a team they're maintaining an average of 110.8 yards on the ground which has them sitting 116th in college football. When it comes to getting in the endzone, the Clemson Tigers are averaging 23.4 points per outing.
The Tigers sit in 43rd in the nation in terms of team defense, allowing 20.2 points per game. Opposing teams are running for an average of 3.4 yards per tote and 108.8 rushing yards per game so far this season. During the season, they have given up 544 rushing yards through 5 outings. When it comes to yards via the pass, the Tigers are giving up 1,174 yards which has them sitting in 73rd in the nation. They have allowed 234.8 yards per outing through the air in addition to conceding a completion percentage of 64.2%. In total, they are conceding 343.6 yards per outing which has them sitting 58th in college football. They have relinquished 5 touchdowns by air in addition to 5 touchdowns via the ground game.
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The Eagles step onto the field holding a record of 1-4 for this season. When they last stepped on the gridiron, the Eagles took a loss by a final score of 48-7 against the Pittsburgh Panthers. Boston College surrendered 43 rush attempts for 172 yds (4.0 yards per rush). The Eagles passing defense gave up a completion rate of 71.1%, surrendering 331 yards on 32 for 45 through the air. The Eagles finished the game with 216 yards while they ran 54 plays (4.0 yds per play). Boston College ran the ball for 1.1 yds per attempt, finishing with a total of 27 yds on 24 carries.
The Boston College Eagles hold an average of 398.4 yards per contest, ranking them 63rd in D-1. The Boston College offense has accrued 270 penalty yards on 34 infractions, which has them ranked 57th in college football in terms of helping out the opposition. They maintain an average of 85.0 yards per game via the rush and have run for 425 yards in total. They have thrown 4 interceptions while surrendering 5 fumbles and they have obtained 101 1st downs. In terms of their scoring prowess, the Eagles are sitting 55th in D-1 by tallying 31.4 PPG. During this campaign so far, the Eagles have thrown for 1,567 passing yards along with holding an average of 313.4 passing yards per outing, putting them at 11th in Division 1.
Boston College has given up a total of 668 yards via the ground game (133.6 yards per game) as well as 7 touchdowns on the ground for the campaign. They have yielded 11 touchdowns through the air as well as 230.8 yards per game, ranking them 85th in D-1. Overall, they have given up 158 total points. Their defense has totaled 1 fumble and 2 interceptions so far this year. The Eagles defense has been on the field for 348 plays, which is 83rd in the nation. The Eagles are conceding 31.6 points per game, which has them sitting 118th in D-1.
Who will win tonight's Tigers/Eagles college football game against the spread?
Josh's Pick: Take the Eagles +14.0
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Additional Resources:
Boston College Eagles - Twitter
Clemson Tigers - Twitter