Duke Blue Devils vs Tulane Green Wave Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
Game: Duke Blue Devils vs Tulane Green Wave
Date: Saturday, September 13, 2025
Location: Yulman Stadium in New Orleans, LA
TV: ESPN/ESPN+
Odds/Point Spread: Green Wave (-3.0)
Total/Over-Under: 53
Yulman Stadium is the location where the Tulane Green Wave (2-0) will attempt to defeat the Duke Blue Devils (1-1) on Saturday, September 13, 2025. Duke opens this game as 3.0-point dogs. The total is 53.
The Duke Blue Devils head into this game 1-1 for this year. The last time they took the field, the Blue Devils faced the Illinois Fighting Illini and took a loss by a score of 45-19. When all was said and done, they had 63 plays which converted into 438 yds. The Duke Blue Devils ended up running the ball 24 times and compiled 82 yds, which earned them an average of 3.4 yards per carry. When it came to stopping the run, the Blue Devils gave up 123 yds on 42 tries, which is an average of 2.9 yds per run allowed. Duke allowed 22 completions on 31 tries for a total of 296 yds, and a completion percentage of 71.0%.

The Blue Devils have attained 986 total yards this season. When it comes to distribution of touchdowns, Duke has totaled 5 touchdowns through the air and 2 rushing touchdowns. They have surrendered the football 6 different times. Duke has accumulated 44 first downs offensively, and they have committed 9 penalties for 84 yds. Offensively they're holding an average of 120.5 yards on the ground which has them sitting 102nd in the country. When it comes to scoring points, the Duke Blue Devils are averaging 32.0 points per game.
When it comes to passing yards, the Blue Devils are allowing 408 yds which has them ranked 71st in the country. They have relinquished 204.0 yards per outing via the pass and allowed a completion percentage of 67.3%. For the season, they are allowing 347.0 yards/outing which puts them 85th in Division 1. They have conceded 3 touchdowns through the air in addition to 5 touchdowns via the ground game. They are giving up 3.3 yards per rushing attempt and 143.0 rushing yards per game this year. During this campaign, they have given up 286 yards via the ground game in 2 games. The Blue Devils are ranked 111th in D-1 when it comes to the opposition scoring, conceding 31.0 PPG.
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The Green Wave head into this game 2-0 for this season. When they last stepped on the field, the Green Wave took home the win by a final score of 33-31 against the South Alabama Jaguars. Tulane relinquished 41 attempts on the ground for 190 yds (4.6 yds per rush). The Green Wave passing defense gave up a completion rate of 70.8%, surrendering 231 yards on 17 out of 24 through the air. The Green Wave finished the game with a total of 406 yards and they ran 72 plays (5.6 yards per play). Tulane rushed the ball for 5.4 yds per carry, finishing the contest with 241 yds on 45 attempts.
When it comes to putting points on the board, the Green Wave currently rank 71st in Division 1 holding an average of 28.0 points per game. The Tulane Green Wave average 413.5 yards per game, ranking them 61st in Division 1. The Tulane offense has compiled 142 yds of penalties on 16 infractions, which is 24th in the nation in terms of helping out the opposition. They have been able to obtain 46 1st downs. During this campaign thus far, the Green Wave have a total of 317 yards through the air in addition to holding an average of 158.5 passing yards per outing, which has them ranked 113th in D-1. They hold an average of 255.0 yards per game via the rush and have toted the ball for 510 yards for the year.
The Green Wave are conceding 17.0 points per game, which puts them 60th in college football. Tulane has surrendered a total of 266 yards via the ground game (133.0 yards/game) and 2 touchdowns via the rush for the year. They have yielded 2 touchdowns through the air as well as 196.0 yards per game, which has them sitting 69th in D-1. The Green Wave defense has participated in 128 plays, which is 64th in the nation. They have tallied 3 fumbles recovered and 4 picks this season.
Who will win tonight's Blue Devils/Green Wave college football game against the spread?
Tony's Pick: Take the Blue Devils +3.0
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Additional Resources:
Tulane Green Wave - Twitter
Duke Blue Devils - Twitter