FIU Panthers vs Penn State Nittany Lions Prediction, 9/6/2025 College Football Picks, Best Bets & Odds

Game: FIU Panthers vs Penn State Nittany Lions

Date: Saturday, September 6, 2025

Location: Beaver Stadium in University Park, PA

TV: BTN

Odds/Point Spread: Nittany Lions (-41.5)

Total/Over-Under: 54.5

The FIU Panthers (1-0) are headed to Beaver Stadium on Saturday, September 6, 2025 where they will attempt to beat the Penn State Nittany Lions (1-0). Penn State opens this matchup as 41.5-point favorites from oddsmakers. The total has been set at 54.5.

The FIU Panthers head into this game 1-0 for this year. In their last contest, the Panthers played against the Bethune-Cookman Wildcats and walked away with a win by a score of 42-9. Once the final whistle blew, they tallied 73 plays which converted into 456 yds. The FIU Panthers ended up rushing 38 times and totaled 223 yards, which earned them an average of 5.9 yds per carry. Against the rush, the Panthers gave up 105 yds on 30 attempts, which averages out to 3.5 yds per rush surrendered. FIU surrendered 23 completions on 39 tries for 241 yds, and a completion percentage of 59.0%.

Regarding putting the ball in the endzone, the FIU Panthers have an average of 42.0 points per outing. As a team they have an average of 223.0 yards in the run game giving them a rank of 34th in D-1. The Panthers have earned 456 total yards for the year. When it comes to notching touchdowns, FIU has compiled 6 rushing touchdowns. FIU has amassed 28 1st downs, and they have been called for 7 infractions for 40 yards. They have turned the ball over 1 time.

Concerning passing yards, the Panthers have conceded 241 yards which has them sitting in 92nd in Division 1. They have yielded 241.0 yards per contest through the air as well as giving up a completion percentage of 59.0%. Over the course of this season, they are allowing 346.0 yards/game which puts them 85th in the country. They have yet to surrender a touchdown on defense. They are giving up an average of 3.5 yards per run and 105.0 rushing yards per contest on the campaign. During this campaign, they have given up 105 running yards through 1 game. The Panthers are ranked 37th in Division 1 in terms of their opponents scoring, conceding 9.0 points per game.

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The Nittany Lions come into this matchup with a record of 1-0 for this season. The last time they took the gridiron, the Nittany Lions took home the win by a final score of 46-11 against the Nevada Wolf Pack. Penn State rushed for 3.8 yds per attempt, totaling 135 yds on 36 carries. The Nittany Lions finished the contest with a total of 438 yds on 71 plays (6.2 yds per play). The Nittany Lions secondary allowed a completion rate of 52.4%, surrendering 125 yards on 11 for 21 through the air. Penn State gave up 31 running attempts for 78 yds (2.5 yards per rush).

Regarding how much they score, the Nittany Lions rank 22nd in D-1 by scoring 46.0 PPG. The Penn State Nittany Lions are averaging 438.0 yards per contest, which ranks them 46th in the nation. The Penn State offense has accrued 45 penalty yards on 5 violations, which is good for 83rd in Division 1 in terms of helping out the other team. They have been able to obtain 25 first downs. For the year thus far, the Nittany Lions have earned 303 passing yards, which ranks 21st in Division 1. They average 135.0 run yards per game.

The Nittany Lions are surrendering 11.0 points per game, which has them 50th in college football. Penn State has conceded a total of 78 yards rushing. They have given up 1 touchdown through the air and 125.0 yards/outing, ranking them 30th in college football. The Nittany Lions defense has been on the field for 52 plays, which ranks 15th in college football. Their defense has totaled 2 fumbles and 1 pick so far this season.

Who will win tonight's Panthers/Nittany Lions college football game against the spread?

Parlays Pundit's Pick: Take the Nittany Lions -41.5

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