Florida Gators vs LSU Tigers Prediction, 9/13/2025 College Football Picks, Best Bets & Odds

Game: Florida Gators vs LSU Tigers

Date: Saturday, September 13, 2025

Location: Tiger Stadium in Baton Rouge, LA

TV: ESPN/ESPN+

Odds/Point Spread: Tigers (-9.5)

Total/Over-Under: 50

The Florida Gators (1-1) are hitting the road to Tiger Stadium on Saturday, September 13, 2025 where they will go up against the LSU Tigers (2-0). LSU opens as 9.5-point favorites. The total is set at 50.

The Florida Gators step onto the field holding a record of 1-1 for this season. In their last game, the Gators went up against the USF Bulls and took a loss by a final of 18-16. The Florida Gators ran the rock 31 different times and accumulated 133 yards, earning them an average of 4.3 yds per carry. Overall, they ran 64 plays for 355 yards. Florida conceded 23 pass completions on 36 attempts for 263 yds, and a completion rate of 63.9%. On the ground, the Gators gave up 128 yards on 29 attempts, which averages out to 4.4 yds per run allowed.

Concerning putting the ball in the endzone, the Florida Gators have an average of 35.5 points per outing. As a unit they average 166.5 yards rushing which has them sitting 69th in college football. The Gators have racked up 806 total yards this season. When it comes to distribution of touchdowns, Florida has amassed 6 passing touchdowns and 1 touchdown on the ground. Florida has amassed 48 first downs as an offense, and they have committed 11 infractions for 103 yds. They have surrendered the football 1 time.

Concerning passing yardage, the Gators are conceding 312 yds which ranks them 40th in college football. They are conceding 156.0 yards per game through the air as well as allowing a completion percentage of 57.4%. During the season, they have surrendered 238.5 yards per outing which ranks them 25th in the country. They have yielded 1 touchdown via the pass. They are allowing 2.7 yards per run and 82.5 yards on the ground per game for the season. In total, they have given up 165 yards via the ground game in 2 games. The Gators rank 20th in Division 1 concerning team defense, allowing 9.0 PPG.

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The Tigers head into this matchup 2-0 for this season. For their last game, the Tigers walked away with a victory by a final of 23-7 against the Louisiana Tech Bulldogs. The Tigers finished the contest with 365 yds while they ran 75 plays (4.9 yds per play). LSU rushed the football for 3.8 yds per carry, finishing the contest with 128 yards on 34 carries. LSU relinquished 27 rushing attempts for 58 yards (2.1 yards per rush). The Tigers secondary gave up a completion percentage of 57.7%, surrendering 96 yds on 15 out of 26 passing.

The LSU Tigers maintain an average of 360.5 yards per contest, which ranks them 84th in the nation. The LSU offense has totaled 122 yards of penalties on 15 violations, which ranks them 37th in the nation in terms of helping out the other team. 1010 They have been able to obtain 52 1st downs. Concerning the points being put on the board, the Tigers currently rank 107th in the country with 20.0 points per contest. During the season thus far, the Tigers have compiled 485 passing yards along with holding an average of 242.5 passing yards per outing, which is ranked 58th in the country.

The Tigers are giving up 8.5 PPG, ranking them 13th in Division 1. LSU has allowed a total of 89 yards on the ground (44.5 yards per contest) and 1 touchdown via the rush on the campaign. They have conceded 1 touchdown via the pass as well as 163.0 yards/outing, ranking them 45th in D-1. The Tigers defense has taken the field for 111 plays, which ranks 21st in Division 1. Their defense has earned 0 fumbles and 1 interception so far this season.

Who will win tonight's Gators/Tigers college football game against the spread?

Guy's Pick: Take the Tigers -9.5

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