Florida State Seminoles vs NC State Wolfpack Prediction, 11/21/2025 College Football Picks, Best Bets & Odds

Game: Florida State Seminoles vs NC State Wolfpack

Date: Friday, November 21, 2025

Location: Carter-Finley Stadium in Raleigh, NC

TV: ESPN

Odds/Point Spread: Wolfpack (+4.5)

Total/Over-Under: 61.5

The Florida State Seminoles (5-5) are en route to Carter-Finley Stadium on Friday, November 21, 2025 where they will attempt to defeat the NC State Wolfpack (5-5). NC State opens as 4.5-point underdogs. The total comes in at 61.5.

The Florida State Seminoles step onto the field holding a record of 5-5 this season. The last time they took the field, the Seminoles played the Virginia Tech Hokies and earned the victory with a final of 34-14. On the day, they had 71 plays which totaled 431 yards. The Florida State Seminoles ended up rushing 46 different times and amassed 237 yds, which is an average of 5.2 yards per tote. When it came to the battle of the line of scrimmage, the Seminoles gave up 238 yds on 41 attempts, which averages out to 5.8 yards per run surrendered. Florida State allowed 10 pass completions on 18 attempts for 125 yds, and a completion rate of 55.6%.

Concerning putting the ball in the endzone, the Florida State Seminoles are averaging 36.4 PPG. As a team they are averaging 227.7 yards on the ground ranking them 9th in the country. The Seminoles have earned 4,875 total yards this season. When it comes to notching touchdowns, Florida State has earned 17 touchdowns through the air and 30 touchdowns via the ground. Florida State has a total of 246 first downs offensively, and they have been hurt by 53 penalties for 479 yds. They have surrendered the football 13 times.

In terms of yards through the air, the Seminoles are allowing 1,969 yards which puts them in 37th in college football. They are giving up 196.9 yards per outing via the pass and giving up a completion percentage of 61.6%. In total, they have surrendered 322.0 yards per outing which ranks them 27th in the nation. They have yielded 15 touchdowns by air as well as 9 touchdowns via the ground game. Opposing teams are running for an average of 3.3 yards per rushing attempt and 125.1 rushing yards per game for the campaign. For the season, they have allowed 1,251 yards on the ground through 10 games. The Seminoles sit in 29th in the nation concerning team defense, giving up 20.3 points per game.

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The Wolfpack come into this matchup with a record of 5-5 this year. When they last played, the Wolfpack took a loss by a score of 41-7 against the Miami Hurricanes. NC State conceded 33 rushing attempts for 151 yds (4.6 yards per rush). The Wolfpack pass defense conceded a completion rate of 67.6%, surrendering 408 yds on 25 for 37 through the air. The Wolfpack finished the contest with 143 yards while they ran 50 plays (2.9 yds per play). NC State ran the ball for 1.2 yds per carry, finishing the game with 23 yards on 20 carries.

When it comes to their scoring prowess, the Wolfpack are sitting 56th in the nation with an average of 29.9 points per game. The NC State Wolfpack have an average of 409.0 yards per outing, which ranks them 51st in the country. The NC State offense has racked up 553 yds of penalties on 58 infractions, which is 92nd in the nation in terms of giving up free yards. They have given away 10 picks while letting opponents recover 3 fumbles and they have recorded 201 1st downs. During this campaign so far, the Wolfpack have thrown for a total of 2,620 yards through the air in addition to an average of 262.0 throwing yards per contest, which has them ranked 35th in Division 1. They have an average of 147.0 rushing yards per game and have rushed for 1,470 yards overall.

NC State has surrendered a total of 1,405 rushing yards (140.5 yards per outing) in addition to 17 touchdowns on the ground on the campaign. They have conceded 18 touchdowns from the passing game in addition to 299.9 yards/outing, ranking them 136th in D-1. Overall, they have conceded 316 pts. They have 3 fumbles recovered and 6 picks on the year. The Wolfpack defense has taken part in 692 plays, ranking them 93rd in the country. The Wolfpack are surrendering 31.6 PPG, which puts them 118th in D-1.

Who will win tonight's Seminoles/Wolfpack college football game against the spread?

Tony's Pick: Take the Seminoles -4.5

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