Jacksonville State Gamecocks vs Southern Miss Golden Eagles Prediction, 9/27/2025 College Football Picks, Best Bets & Odds

Game: Jacksonville State Gamecocks vs Southern Miss Golden Eagles

Date: Saturday, September 27, 2025

Location: M. M. Roberts Stadium in Hattiesburg, MS

TV: ESPN+

Odds/Point Spread: Golden Eagles (-5.0)

Total/Over-Under: 57

M. M. Roberts Stadium is the location where the Southern Miss Golden Eagles (2-2) will take on the Jacksonville State Gamecocks (2-2) on Saturday, September 27, 2025. Southern Miss opens this game as 5.0-point favorites. The over/under is set at 57.

The Jacksonville State Gamecocks head into this game 2-2 for this season. The last time they took the field, the Gamecocks stepped onto the field against the Murray State Racers and went home with a win by a final score of 45-10. When it came to stopping the run, the Gamecocks gave up 92 yds on 35 tries, which averages out to 2.6 yards per rush allowed. Jacksonville State gave up 21 pass completions on 33 tries for 141 yds, and a completion percentage of 63.6%. In the game, they ran 79 plays for 531 yds. The Jacksonville State Gamecocks ran the ball 45 times and had 329 yards, which is an average of 7.3 yards per carry.

Regarding scoring points, the Jacksonville State Gamecocks are averaging 30.8 points per game. As a team they have an average of 261.3 yards on the ground ranking them 8th in D-1. The Gamecocks have earned 1,639 total yards for the year. When it comes to distribution of touchdowns, Jacksonville State has earned 2 touchdowns via the pass and 13 touchdowns on the ground. Jacksonville State has amassed 87 1st downs, and they have been called for 19 infractions for 184 yards. They have surrendered the football 3 times.

Concerning passing yards, the Gamecocks are giving up 981 yds which puts them in 108th in Division 1. They have given up 245.3 yards per contest via the pass in addition to allowing a completion percentage of 65.4%. For the year, they are granting 399.8 yards per contest putting them at 104th in D-1. They have yielded 5 touchdowns by air and 4 touchdowns running the ball. The opposition is running for an average of 4.1 yards per running attempt and 154.5 rushing yards per game for the campaign. Over the course of this year, they have conceded 618 yards via the running game in 4 outings. The Gamecocks sit in 71st in Division 1 in terms of team defense, allowing 23.0 points per game.

Get all of our College Football Picks Against the Spread

The Golden Eagles come into this game with a record of 2-2 for this season. The last time they took the field, the Golden Eagles walked away with a loss by a score of 30-20 against the Louisiana Tech Bulldogs. The Golden Eagles finished the contest with a total of 514 yds on 82 plays (6.3 yards per play). Southern Miss ended up running for 3.5 yds per carry, finishing with a total of 122 yds on 35 carries. Southern Miss relinquished 38 attempts on the ground for 101 yds (2.7 yards per carry). The Golden Eagles secondary gave up a completion rate of 71.4%, surrendering 238 yds on 15 out of 21 passing.

The Southern Miss Golden Eagles hold an average of 391.8 yards per game, which ranks them 71st in the nation. The Southern Miss offense has 231 yards of penalties on 29 violations, which has them sitting 23rd in D-1 in terms of making mistakes. They hold an average of 118.3 run yards per game and have toted the ball for 473 yards overall. They have tossed 3 picks while surrendering 0 fumbles and they have been able to obtain 90 1st downs. Concerning the points being put on the board, the Golden Eagles rank 78th in D-1 averaging 28.3 points per outing. For the year thus far, the Golden Eagles have racked up 1,094 yards through the air in addition to holding an average of 273.5 passing yards per contest, putting them at 32nd in D-1.

Southern Miss has surrendered a total of 573 yards via the ground game (143.3 yards/game) and 10 touchdowns via the rush on the campaign. They have allowed the opposition 2 touchdowns via the pass in addition to 255.8 yards/outing, ranking them 109th in college football. This season, they have relinquished 106 pts. Their defense has compiled 0 fumbles recovered and 6 picks this year. The Golden Eagles defense has taken the field for 296 plays, which ranks 128th in college football. The Golden Eagles are conceding 26.5 points per game, which has them ranked 90th in Division 1.

Who will win tonight's Gamecocks/Golden Eagles college football game against the spread?

Tony's Pick: Take the Golden Eagles -5.0

Get $60 worth of FREE premium member picks. No Obligation. No Salesman. No Credit Card. Fast Sign up with Instant Access Click Here