Louisiana Ragin' Cajuns vs Missouri Tigers Prediction, 9/13/2025 College Football Picks, Best Bets & Odds

Game: Louisiana Ragin' Cajuns vs Missouri Tigers

Date: Saturday, September 13, 2025

Location: Memorial Stadium in Columbia, MO

TV: ESPN/ESPN+

Odds/Point Spread: Tigers (-27.5)

Total/Over-Under: 49.5

The Louisiana Ragin' Cajuns (1-1) are headed to Memorial Stadium on Saturday, September 13, 2025 where they will play the Missouri Tigers (2-0). Missouri opens this game as 27.5-point favorites. The over/under comes in at 49.5.

The Louisiana Ragin' Cajuns head into this game 1-1 for this season. The last time they took the field, the Ragin' Cajuns took the field against the McNeese State Cowboys and took home the win by a score of 34-10. In the running game, the Ragin' Cajuns gave up 47 yards on 26 attempts, which averages out to 1.8 yds per run surrendered. Louisiana allowed 19 completions on 30 tries for a total of 191 yds, and a completion rate of 63.3%. When all was said and done, they ran 67 plays which totaled 401 yds. The Louisiana Ragin' Cajuns ran the rock 45 times and amassed 315 yards, earning them an average of 7.0 yds per attempt.

Concerning putting the ball in the endzone, the Louisiana Ragin' Cajuns are averaging 23.0 points per game. As a unit they maintain an average of 233.0 yards on the ground which ranks them 24th in the country. The Ragin' Cajuns have racked up 640 total yards for this campaign. When it comes to getting the ball in the endzone, Louisiana has compiled 1 touchdown through the air and 4 rushing touchdowns. Louisiana has amassed 41 first downs, and they have been called for 12 penalties for 99 yards. They have surrendered the ball 2 times.

Regarding yards through the air, the Ragin' Cajuns are allowing 236 yards which puts them in 17th in the nation. They have given up 118.0 yards per contest via the pass as well as conceding a completion percentage of 66.7%. During the season, they have given up 244.5 yards/contest putting them at 29th in the country. They have allowed 3 touchdowns via the ground game. Opposing teams are running for an average of 3.1 yards per running attempt and 126.5 yards on the ground per game on the campaign. In total, they have conceded 253 rushing yards through 2 games. The Ragin' Cajuns sit in 37th in D-1 in terms of team defense, allowing 12.0 points per game.

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The Tigers step onto the field holding a record of 2-0 this season. For their last game, the Tigers took home the win by a final score of 42-31 when they faced the Kansas Jayhawks. Missouri rushed the football for 5.6 yards per carry, totaling 261 yds on 47 carries. The Tigers finished the contest with 595 yds while running 86 plays (6.9 yards per play). The Tigers passing defense conceded a completion percentage of 60.0%, relinquishing 223 yds on 18 out of 30 through the air. Missouri conceded 19 rushing attempts for 28 yards (1.5 yds per rush).

The Missouri Tigers have an average of 577.5 yards per outing, which has them ranked 5th in Division 1. The Missouri offense has racked up 140 penalty yds on 15 violations, which is good for 30th in college football in terms of hurting your team. They are averaging 240.0 rushing yards per game and have run for 480 yards overall. They have been able to tally 53 1st downs. Regarding putting points on the board, the Tigers are 11th in Division 1 by scoring 51.5 points per contest. During the season thus far, the Tigers have a total of 675 passing yards not to mention an average of 337.5 passing yards per game, which ranks 12th in the nation.

The Tigers are surrendering 18.5 PPG, which puts them 63rd in D-1. Missouri has yielded a total of 182 yards on the ground (91.0 yards per contest) in addition to 1 touchdown via the rush on the season. They have given up 3 touchdowns through the air and 148.0 yards/game, which has them in 34th in college football. The Tigers defense has taken part in 111 plays, which is good for 22nd in college football. They have earned 1 fumble recovery and 2 picks so far this year.

Who will win tonight's Ragin' Cajuns/Tigers college football game against the spread?

Tony's Pick: Take the Tigers -27.5

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