Minnesota Golden Gophers vs Ohio State Buckeyes Prediction, 10/4/2025 College Football Picks, Best Bets & Odds

Game: Minnesota Golden Gophers vs Ohio State Buckeyes

Date: Saturday, October 4, 2025

Location: Ohio Stadium in Columbus, OH

TV: NBC Peacock

Odds/Point Spread: Buckeyes (-24.0)

Total/Over-Under: 44.5

Ohio Stadium is where the Ohio State Buckeyes (4-0) will attempt to beat the Minnesota Golden Gophers (3-1) on Saturday, October 4, 2025. Ohio State opens this contest as 24.0-point favorites from oddsmakers. The total has been set at 44.5.

The Minnesota Golden Gophers come into this matchup with a record of 3-1 for this season. In their last matchup, the Golden Gophers took on the Rutgers Scarlet Knights and went home with a win by a final score of 31-28. The Minnesota Golden Gophers ended up rushing 18 different times and totaled 35 yards, earning them an average of 1.9 yards per attempt. For the game, they ran 59 plays which gave them 359 yards. Minnesota allowed 21 completions on 34 tries for a total of 249 yards, and a completion rate of 61.8%. Against the run, the Golden Gophers gave up 138 yds on 42 tries, which averages out to 3.3 yards per run allowed.

The Golden Gophers have racked up 1,621 yards in total this season. In terms of getting the ball in the endzone, Minnesota has compiled 8 touchdowns through the air and 7 rushing touchdowns. They have surrendered the ball 4 different times. Minnesota has amassed 91 first downs as a unit, and they have committed 17 penalties for 170 yards. As a team they're averaging 144.0 yards on the ground which is 88th in college football. When talking about putting points on the board, the Minnesota Golden Gophers are averaging 33.5 points per outing.

When talking about yards through the air, the Golden Gophers are allowing 658 yards which puts them in 16th in Division 1. They have given up 164.5 yards per game via the pass and allowed a completion percentage of 61.1%. Over the course of this season, they are conceding 230.0 yards per game which has them ranked 9th in D-1. They have yielded 6 touchdowns through the air in addition to 2 touchdowns on the ground. The opposition is running for 2.3 yards per run and 65.5 rushing yards per contest for the season. In total, they have conceded 262 yards via the running game in 4 games. The Golden Gophers rank 25th in Division 1 when it comes to team defense, giving up 16.3 points per game.

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The Buckeyes head into this matchup 4-0 this season. When they last stepped on the gridiron, the Buckeyes went home victorious with a score of 24-6 when they faced the Washington Huskies. Ohio State ran for 4.4 yards per tote, finishing the game with 149 yds on 34 carries. The Buckeyes finished the game with a total of 357 yds and they ran 62 plays (5.8 yards per play). The Buckeyes secondary gave up a completion percentage of 78.3%, relinquishing 173 yards on 18 for 23 passing. Ohio State conceded 30 rush attempts for 61 yds (2.0 yds per rush).

The Ohio State Buckeyes hold an average of 445.8 yards per contest, which ranks them 33rd in the nation. The Ohio State offense has totaled 140 penalty yards on 16 infractions, which has them sitting 127th in the nation in terms of helping out the opposition. They hold an average of 181.3 rushing yards per game and have toted the ball for 725 yards in total. They have given away 3 interceptions while surrendering 1 fumble and they have been able to tally 93 first downs. When looking at their scoring prowess, the Buckeyes rank 37th in D-1 by scoring 36.3 points per game. Over the course of the season to this point, the Buckeyes have thrown for 1,058 yards via the pass in addition to holding an average of 264.5 passing yards per game, which is ranked 40th in the country.

Ohio State has yielded a total of 389 yards rushing (97.3 yards per game) in addition to 0 touchdown rushing for the campaign. They have allowed 2 touchdowns through the air in addition to 132.0 yards/contest, which has them sitting 8th in the nation. Overall, they have relinquished 22 pts. They have earned 3 fumbles recovered and 2 picks on the year. The Buckeyes defense has been on the field for 230 plays, which is good for 8th in D-1. The Buckeyes are allowing 5.5 PPG, which puts them 1st in Division 1.

Who will win tonight's Golden Gophers/Buckeyes college football game against the spread?

Guy's Pick: Take the Buckeyes -24.0

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