Mississippi State Bulldogs vs Missouri Tigers Prediction, 11/15/2025 College Football Picks, Best Bets & Odds

Game: Mississippi State Bulldogs vs Missouri Tigers

Date: Saturday, November 15, 2025

Location: Memorial Stadium in Columbia, MO

TV: SEC Network

Odds/Point Spread: Tigers (-6.5)

Total/Over-Under: 52

The Mississippi State Bulldogs (5-4) are traveling to Memorial Stadium on Saturday, November 15, 2025 where they will take on the Missouri Tigers (6-2). Mississippi State opens this game as 6.5-point dogs. The over/under has been set at 52.

The Mississippi State Bulldogs step onto the field holding a record of 5-4 for this year. The last time they stepped onto the field, the Bulldogs faced off with the Georgia Bulldogs and went home with a loss by a final score of 41-21. When it came to stopping the run, the Bulldogs gave up 303 yards on 44 attempts, which is an average of 6.9 yards per run allowed. Mississippi State relinquished 18 completions on 30 tries for a total of 264 yds, and a completion rate of 60.0%. In all, they ran 68 plays which gave them 322 yds. The Mississippi State Bulldogs ran the football 43 different times and amassed 149 yds, which earned them an average of 3.5 yards per carry.

The Bulldogs have earned 3,674 total yards for the year. When it comes to getting in the endzone, Mississippi State has amassed 18 passing touchdowns and 21 rushing touchdowns. They have turned the football over 10 times. Mississippi State has compiled 198 first downs as a unit, and they have been flagged for 69 infractions for 593 yards. As a team they are averaging 157.7 yards on the ground ranking this team at 66th in D-1. Regarding getting in the endzone, the Mississippi State Bulldogs are sitting at 33.2 PPG.

The Bulldogs sit in 73rd in D-1 concerning the opposition scoring, allowing 24.7 points per contest. They are allowing 4.3 yards per attempt on the ground and 162.1 rushing yards per contest on the campaign. Overall, they have allowed 1,459 rushing yards through 9 games. In terms of passing yardage, the Bulldogs are allowing 1,861 yds which ranks them 67th in college football. They have yielded 206.8 yards per game through the air as well as allowing a completion percentage of 60.2%. For the season, they are conceding 368.9 yards per outing putting them 69th in the nation. They have yielded 12 touchdowns via the pass as well as 11 touchdowns on the ground.

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The Tigers come into this game with a record of 6-2 for this season. When they last stepped on the gridiron, the Tigers took a defeat with a final score of 38-17 when they played the Texas A&M Aggies. Missouri ran for 6.1 yards per attempt, finishing the contest with 207 yds on 34 attempts. The Tigers finished with 284 yds on 56 plays (5.1 yds per play). The Tigers pass defense gave up a completion percentage of 69.0%, surrendering 221 yds on 20 for 29 through the air. Missouri allowed 39 attempts on the ground for 243 yards (6.2 yards per rush).

The Missouri Tigers are averaging 472.8 yards per outing, which has them sitting 14th in Division 1. The Missouri offense has totaled 417 penalty yards on 40 infractions, ranking them 115th in D-1 in terms of giving up free yards. They average 235.5 yards per game via the rush and have toted the ball for 1,884 yards for this season. They have thrown 7 interceptions while losing 2 fumbles and they have been able to earn 207 1st downs. When discussing how much they score, the Tigers are 26th in Division 1 by scoring 35.4 points per outing. For the year so far, the Tigers currently have a total of 1,898 yards through the air in addition to an average of 237.3 passing yards per game, which has them sitting 63rd in Division 1.

The Tigers are giving up 16.8 points per game, which has them 13th in college football. Missouri has conceded a total of 723 yards on the ground (90.4 yards per contest) as well as 6 touchdowns on the ground on the year. They have allowed the opposition 9 touchdowns via the pass and 155.4 yards/contest, ranking them 7th in Division 1. The Tigers defense has taken the field for 443 plays, which has them sitting 1st in college football. Their defense has 2 fumbles recovered and 5 interceptions this season. This season, they have given up 134 points in total.

Who will win tonight's Bulldogs/Tigers college football game against the spread?

Guy's Pick: Take the Bulldogs +6.5

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