Nevada Wolf Pack vs Western Kentucky Hilltoppers Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

Game: Nevada Wolf Pack vs Western Kentucky Hilltoppers

Date: Saturday, September 20, 2025

Location: Houchens Industries in Bowling Green, KY

TV: ESPN/ESPN+

Odds/Point Spread: Hilltoppers (-10.5)

Total/Over-Under: 55.5

The Nevada Wolf Pack (1-2) are en route to Houchens Industries on Saturday, September 20, 2025 where they will attempt to defeat the Western Kentucky Hilltoppers (2-1). Western Kentucky opens this contest as 10.5-point favorites. The total comes in at 55.5.

The Nevada Wolf Pack head into this game 1-2 for this season. In their last contest, the Wolf Pack faced the MTSU Blue Raiders and went home with a loss by a final score of 14-13. When all was said and done, they ran 60 plays which gave them 369 yards. The Nevada Wolf Pack ran the football 35 times and tallied 203 yds, which had them averaging 5.8 yards per tote. When it came to stopping the run, the Wolf Pack conceded 105 yards on 30 attempts, which averages out to 3.5 yds per rush allowed. Nevada relinquished 27 pass completions on 45 attempts for a total of 247 yds, and a completion percentage of 60.0%.

The Wolf Pack have earned 985 total yards for this campaign. In terms of scoring touchdowns, Nevada has amassed 2 touchdowns through the air and 1 touchdown on the ground. They have turned the football over 7 times. Nevada has accounted for 52 1st downs offensively, and they have been hurt by 14 penalties for 131 yds. Offensively they're maintaining an average of 183.3 yards in the run game ranking this team at 50th in D-1. In terms of scoring, the Nevada Wolf Pack are sitting at 14.7 points per game.

In terms of passing yards, the Wolf Pack have conceded 775 yards which ranks them 112th in the nation. They have given up 258.3 yards per outing via the pass in addition to conceding a completion percentage of 70.6%. During this campaign, they are conceding 387.0 yards per contest which ranks them 96th in college football. They have surrendered 3 touchdowns through the air and 6 touchdowns via the ground game. They are giving up an average of 3.6 yards per run and 128.7 yards on the ground per game on the year. In total, they have given up 386 yards via the ground game in 3 games. The Wolf Pack rank 91st in D-1 when it comes to team defense, giving up 25.7 points per contest.

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The Hilltoppers come into this matchup with a record of 2-1 for this season. In their last game, the Hilltoppers walked away with a loss by a score of 45-21 when they played the Toledo Rockets. The Hilltoppers finished with 333 yds while running 67 plays (5.0 yds per play). Western Kentucky ran the football for 2.1 yards per tote, finishing with 59 yards on 28 attempts. Western Kentucky gave up 42 rushing attempts for 307 yds (7.3 yards per carry). The Hilltoppers pass defense conceded a completion rate of 57.1%, relinquishing 201 yards on 12 for 21 passing.

In terms of their ability to score points, the Hilltoppers are 37th in the country maintaining an average of 39.0 points per contest. The Western Kentucky Hilltoppers are averaging 467.3 yards per contest, which has them sitting 31st in D-1. The Western Kentucky offense has totaled 192 penalty yards on 18 violations, which ranks 58th in college football in terms of giving up free yards. They have tossed 1 interception while losing 3 fumbles and they have been able to tally 70 first downs. During this campaign to this point, the Hilltoppers have thrown for a total of 1,074 passing yards in addition to an average of 358.0 passing yards per contest, ranking them 8th in the country. They hold an average of 109.3 yards via the ground game and have toted the ball for 328 yards in total.

Western Kentucky has given up a total of 633 yards via the ground game (211.0 yards per outing) and 4 touchdowns via the rush for the year. They have given up 3 touchdowns via the pass and 171.7 yards/outing, which has them sitting 35th in D-1. In total, they have allowed 75 points. Their defense has compiled 1 fumble recovered and 2 picks for the season. The Hilltoppers defense has taken the field for 196 plays, which has them sitting 72nd in the nation. The Hilltoppers are relinquishing 25.0 points per game, which has them ranked 87th in the nation.

Who will win tonight's Wolf Pack/Hilltoppers college football game against the spread?

Josh's Pick: Take the Hilltoppers -10.5

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