Northwestern Wildcats vs Nebraska Cornhuskers Prediction, 10/25/2025 College Football Picks, Best Bets & Odds
Game: Northwestern Wildcats vs Nebraska Cornhuskers
Date: Saturday, October 25, 2025
Location: Memorial Stadium in Lincoln, NE
TV: FS1
Odds/Point Spread: Cornhuskers (-7.0)
Total/Over-Under: 43.5
The Northwestern Wildcats (5-2) are headed to Memorial Stadium on Saturday, October 25, 2025 where they will take on the Nebraska Cornhuskers (5-2). Northwestern opens this matchup as 7.0-point underdogs. The total comes in at 43.5.
The Northwestern Wildcats come into this matchup with a record of 5-2 this season. The last time they stepped onto the field, the Wildcats played against the Purdue Boilermakers and earned the victory with a final of 19-0. Against the run, the Wildcats conceded 87 yards on 26 attempts, which is an average of 3.3 yards per rush surrendered. Northwestern allowed 16 pass completions on 30 attempts for 218 yds, and a completion rate of 53.3%. In the game, they ran 76 plays which converted into 364 yards. The Northwestern Wildcats ended up running the ball 50 different times and recorded 232 yards, which had them averaging 4.6 yards per tote.

The Wildcats have tallied 2,551 total yards this season. In terms of getting in the endzone, Northwestern has totaled 10 touchdowns via the pass and 8 rushing touchdowns. They have given the ball to the opposition 11 different times. Northwestern has tallied 152 1st downs as an offense, and they have been flagged for 27 penalties for 199 yards. As a team they're averaging 190.1 yards on the ground which ranks them 38th in the country. Regarding putting points on the board, the Northwestern Wildcats are averaging 22.7 points per contest.
Regarding passing yards, the Wildcats are conceding 1,180 yds which has them ranked 20th in the country. They have conceded 168.6 yards per game via the pass as well as allowing a completion percentage of 58.6%. For the season, they have yielded 305.3 yards/outing which ranks them 22nd in college football. They have granted 5 touchdowns by air as well as 7 touchdowns pounding the rock. They are allowing an average of 4.5 yards per rush and 136.7 rushing yards per contest so far this season. Over the course of this year, they have allowed 957 yards via the ground game in 7 contests. The Wildcats are ranked 11th in college football regarding their opponents scoring, allowing 15.1 points per game.
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The Cornhuskers come into this game with a record of 5-2 for this season. When they last stepped on the field, the Cornhuskers walked away with a loss by a score of 24-6 when they played the Minnesota Golden Gophers. Nebraska allowed 35 attempts on the ground for 186 yds (5.3 yds per rush). The Cornhuskers passing defense allowed a completion percentage of 80.0%, surrendering 153 yards on 16 out of 20 passing. The Cornhuskers finished the game with 213 yards and they ran 54 plays (3.9 yds per play). Nebraska ended up running for 1.2 yards per tote, finishing with 36 yards on 29 carries.
The Nebraska Cornhuskers hold an average of 416.1 yards per game, ranking them 51st in D-1. The Nebraska offense has accrued 310 yds of penalties on 34 infractions, which ranks 107th in the country in terms of helping out the other team. They average 125.0 yards per game via the rush and have toted the ball for 875 yards for the season. They have thrown 5 picks while conceding 1 fumbles and they have been able to obtain 158 first downs. Regarding how much they score, the Cornhuskers rank 29th in D-1 averaging 36.0 PPG. During the season to this point, the Cornhuskers have compiled 2,038 yards via the pass not to mention an average of 291.1 throwing yards per contest, which has them sitting 18th in D-1.
The Cornhuskers are giving up 19.4 PPG, which has them ranked 30th in college football. Nebraska has allowed a total of 1,094 rushing yards (156.3 yards per game) and 13 touchdowns rushing for the season. They have given up 3 touchdowns from the passing game as well as 123.0 yards/outing, which puts them in 1st in the nation. The Cornhuskers defense has been on the field for 413 plays, which ranks 20th in the country. They have compiled 6 fumbles and 3 interceptions on the year. This year, they have given up 136 points in total.
Who will win tonight's Wildcats/Cornhuskers college football game against the spread?
Tony's Pick: Take the Wildcats +7.0
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Additional Resources:
Nebraska Cornhuskers - Twitter
Northwestern Wildcats - Twitter