Oklahoma State Cowboys vs Texas Tech Red Raiders Prediction, 10/25/2025 College Football Picks, Best Bets & Odds

Game: Oklahoma State Cowboys vs Texas Tech Red Raiders

Date: Saturday, October 25, 2025

Location: Jones AT&T Stadium in Lubbock, TX

TV: ESPNU

Odds/Point Spread: Red Raiders (-38.5)

Total/Over-Under: 56.5

The Texas Tech Red Raiders (6-1) are welcoming the Oklahoma State Cowboys (1-6) at Jones AT&T Stadium on Saturday, October 25, 2025. Oklahoma State opens as 38.5-point underdogs from Vegas oddsmakers. The total has been set at 56.5.

The Oklahoma State Cowboys head into this matchup 1-6 this season. In their last matchup, the Cowboys faced off with the Cincinnati Bearcats and took a loss by a final of 49-17. When it came to stopping the run, the Cowboys conceded 157 yds on 31 attempts, which is an average of 5.1 yds per run surrendered. Oklahoma State allowed 20 pass completions on 29 tries for 270 yards, and a completion percentage of 69.0%. In all, they ran 67 plays which gave them 377 yards. The Oklahoma State Cowboys ended up rushing 48 different times and had 228 yards, earning them an average of 4.8 yds per carry.

When it comes to getting in the endzone, the Oklahoma State Cowboys have an average of 16.6 PPG. As a team they average 139.3 yards in the run game which has them sitting 92nd in D-1. The Cowboys have earned 2,181 yards in total this season. In terms of getting the ball in the endzone, Oklahoma State has earned 4 touchdowns through the air and 7 touchdowns on the ground. Oklahoma State has a total of 113 1st downs as a team, and they have been flagged for 47 penalties for 434 yds. They have surrendered the ball 7 times.

The Cowboys rank 132nd in D-1 concerning team defense, allowing 38.4 points per game. Opposing teams are running for an average of 4.6 yards per rushing attempt and 174.3 rushing yards per game this season. Over the course of this season, they have given up 1,220 yards via the ground game in 7 outings. In terms of passing yards, the Cowboys have conceded 2,062 yards which has them sitting in 131st in the country. They are giving up 294.6 yards per contest via the pass in addition to giving up a completion percentage of 68.4%. In total, they have allowed 468.9 yards per outing which ranks them 134th in college football. They have surrendered 19 touchdowns by air as well as 12 touchdowns via the ground game.

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The Red Raiders head into this game 6-1 for this season. The last time they took the field, the Red Raiders went home defeated by a final of 26-22 against the Arizona State Sun Devils. Texas Tech surrendered 36 attempts on the ground for 75 yds (2.1 yds per rush). The Red Raiders passing defense gave up a completion rate of 59.6%, surrendering 319 yards on 28 out of 47 through the air. The Red Raiders finished the contest with 276 yds while they ran 65 plays (4.2 yards per play). Texas Tech rushed the ball for 4.0 yards per attempt, finishing the contest with 109 yds on 27 attempts.

When discussing their scoring prowess, the Red Raiders sit 4th in Division 1 scoring 43.9 points per game. The Texas Tech Red Raiders maintain an average of 517.9 yards/contest, ranking them 3rd in D-1. The Texas Tech offense has 498 yards of penalties on 57 infractions, which is good for 8th in the country in terms of helping out the other team. They have given away 6 picks while surrendering 2 fumbles and they have tallied 175 first downs. For the year thus far, the Red Raiders currently sit at 2,119 passing yards in addition to an average of 302.7 passing yards per game, which has them ranked 9th in Division 1. They average 215.1 run yards per game and have run for 1,506 yards for the season.

Texas Tech has given up a total of 450 yards rushing (64.3 yards/game) as well as 3 touchdowns on the ground for the year. They have allowed 8 touchdowns through the air and 212.1 yards per contest, which has them ranked 55th in the nation. In total, they have conceded 99 total points. Their defense has earned 5 fumbles recovered and 8 picks so far this season. The Red Raiders defense has taken the field for 470 plays, which is good for 85th in Division 1. The Red Raiders are conceding 14.1 PPG, which has them ranked 6th in the nation.

Who will win tonight's Cowboys/Red Raiders college football game against the spread?

Guy's Pick: Take the Red Raiders -38.5

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